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Gp2 Gene Detail
Summary
  • Symbol
    Gp2
  • Name
    glycoprotein 2 (zymogen granule membrane)
  • Synonyms
    2310037I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914383
    NCBI Gene: 67133
  • Gene Overview
    MyGene.info: GP2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:119442542-119459272 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 63.88 cM, cytoband F1-F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914383
protein coding gene Chr7:119442537-119459285 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032909
protein coding gene Chr7:123338933-123355571 (-)
A/J MGP_AJ_G0032892
protein coding gene Chr7:120172730-120189216 (-)
AKR/J MGP_AKRJ_G0032824
protein coding gene Chr7:123269514-123286157 (-)
BALB/cJ MGP_BALBcJ_G0032897
protein coding gene Chr7:119893935-119911025 (-)
C3H/HeJ MGP_C3HHeJ_G0032607
protein coding gene Chr7:123159430-123175911 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033403
protein coding gene Chr7:128229891-128251247 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030375
protein coding gene Chr7:121607367-121623787 (-)
CAST/EiJ MGP_CASTEiJ_G0031935
protein coding gene Chr7:114922469-114938935 (-)
CBA/J MGP_CBAJ_G0032580
protein coding gene Chr7:132524378-132540869 (-)
DBA/2J MGP_DBA2J_G0032732
protein coding gene Chr7:118213278-118230244 (-)
FVB/NJ MGP_FVBNJ_G0032685
protein coding gene Chr7:118055479-118072103 (-)
LP/J MGP_LPJ_G0032826
protein coding gene Chr7:124808978-124830718 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032717
protein coding gene Chr7:133977656-134021041 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033423
protein coding gene Chr7:122243889-122260097 (-)
PWK/PhJ MGP_PWKPhJ_G0031643
protein coding gene Chr7:111130829-111147474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031490
protein coding gene Chr7:108994570-109030754 (-)
WSB/EiJ MGP_WSBEiJ_G0032048
protein coding gene Chr7:123147943-123166740 (-)



Homology
more
  • Human Ortholog
    GP2, glycoprotein 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GP2, glycoprotein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZAP75
  • Links
    NCBI Gene ID: 2813
    neXtProt AC: NX_P55259
    UniProt: P55259

  • Chr Location
    16p12.3; chr16:20309574-20327805 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Homozygous null mice display no obvious abnormalities in pancreas morphology and function, development, growth, weight, behavior, life span, or fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67133 NCBI Gene Model | MGI Sequence Detail 16731 C57BL/6J ±  kb
transcript NM_025989 RefSeq | MGI Sequence Detail 1978 C57BL/6  
polypeptide Q9D733 UniProt | EBI | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site
    IPR001507 Zona pellucida domain
Molecular
Reagents
less
  • All nucleic 28
    Genomic 2
    cDNA 26

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142175
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:238004 Iwasaki M, et al., Residues K465 and G467 within the Cytoplasmic Domain of GP2 Play a Critical Role in the Persistence of Lymphocytic Choriomeningitis Virus in Mice. J Virol. 2016 Nov 15;90(22):10102-10112

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory