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Gp2 Gene Detail
Summary
  • Symbol
    Gp2
  • Name
    glycoprotein 2 (zymogen granule membrane)
  • Synonyms
    2310037I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914383
    NCBI Gene: 67133
  • Gene Overview
    MyGene.info: GP2
Location & Maps
more
  • Sequence Map
    Chr7:119442537-119459285 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16749 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 63.88 cM, cytoband F1-F2
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GP2, glycoprotein 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GP2, glycoprotein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ZAP75
  • Links
    NCBI Gene ID: 2813
    neXtProt AC: NX_P55259

  • Chr Location
    16p12; chr16:20309574-20327820 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Homozygous null mice display no obvious abnormalities in pancreas morphology and function, development, growth, weight, behavior, life span, or fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059101 VEGA Gene Model | MGI Sequence Detail 16749 C57BL/6J ±  kb
transcript OTTMUST00000144960 VEGA | MGI Sequence Detail 1853 Not Applicable  
polypeptide OTTMUSP00000075515 VEGA | MGI Sequence Detail 556 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    177 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site
    IPR001507 Zona pellucida domain
Molecular
Reagents
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  • All nucleic 27
    Genomic 1
    cDNA 26

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142175
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:188796 de Lau W, et al., Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". Mol Cell Biol. 2012 Sep;32(18):3639-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory