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Nrarp
Gene Detail
Symbol

Name
ID
Nrarp
Notch-regulated ankyrin repeat protein
MGI:1914372
Synonyms
2700054M22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
17.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:25180758-25183339 bp, + strand
From VEGA annotation of GRCm38

  2582 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: NRARP
Gene Tree: Nrarp

Human
homologs
NRARP, Notch-regulated ankyrin repeat protein
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 441478
neXtProt AC: NX_Q7Z6K4

Human Chr (Location): 9q34.3; chr9:137299631-137302251 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit delayed retinal vascularization due to increased vascular regression. Mice homozygous for a different knock-out allele exhibit vertebral and rib fusions.
 
Interactions
Nrarp interacts with 181 markers (Mir1b, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (22 records)
Data Summary: Results (289)    Tissues (75)    Images (115)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 279
Northern blot 8
RT-PCR 2
cDNA source data(47)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA NRARP ; Xenbase nrarp ; ZFIN nrarpa, nrarpb    NEW 
Molecular
reagents
All nucleic(53) cDNA(48) Primer pair(2) Other(3)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000011778 (Evidence)
Ensembl Gene Model ENSMUSG00000078202 (Evidence)
Entrez Gene 67122 (Evidence)
UniGene 46539
DFCI TC1579866, TC1596421
DoTS DT.94157303, DT.91412317, DT.489864
NIA Mouse Gene Index U001476
Consensus CDS Project CCDS38066.1
International Mouse Phenotyping Consortium Status Nrarp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011778 VEGA Gene Model | MGI Sequence Detail 2582 C57BL/6J ±  kb
transcript OTTMUST00000027642 VEGA | MGI Sequence Detail 2582 Not Applicable 
polypeptide OTTMUSP00000012558 VEGA | MGI Sequence Detail 114 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
Protein Ontology PR:000011415 notch-regulated ankyrin repeat-containing protein
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(49)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory