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Bfar Gene Detail
Summary
  • Symbol
    Bfar
  • Name
    bifunctional apoptosis regulator
  • Synonyms
    RNF47
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914368
    NCBI Gene: 67118
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:13489722-13521476 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 9.45 cM, cytoband B1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    753 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914368
 protein coding gene Chr16:13489722-13521476 (+)
129S1/SvImJ ENSMUSG00200041597
 protein coding gene Chr16:10472229-10503803 (+)
A/J ENSMUSG00195032037
 protein coding gene Chr16:10037281-10068861 (+)
AKR/J ENSMUSG00220043572
 protein coding gene Chr16:10334154-10365730 (+)
BALB/cJ ENSMUSG00180037013
 protein coding gene Chr16:10278519-10310422 (+)
C3H/HeJ ENSMUSG00175042855
 protein coding gene Chr16:10437624-10469946 (+)
C57BL/6NJ ENSMUSG00215030651
 protein coding gene Chr16:10154252-10185980 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020467
 protein coding gene Chr16:10164606-10195407 (+)
CAST/EiJ ENSTCUG00005041460
 protein coding gene Chr16:10335797-10367440 (+)
CBA/J ENSMUSG00210034688
 protein coding gene Chr16:10454594-10486915 (+)
DBA/2J ENSMUSG00185031229
 protein coding gene Chr16:10400130-10432452 (+)
FVB/NJ ENSMUSG00205021272
 protein coding gene Chr16:10394265-10425842 (+)
JF1/MsJ ENSUMUG00000037614
 protein coding gene Chr16:10505796-10544640 (+)
LP/J ENSMUSG00230043730
 protein coding gene Chr16:12967783-12999359 (+)
NOD/ShiLtJ ENSMUSG00190038934
 protein coding gene Chr16:10528994-10560750 (+)
NZO/HlLtJ ENSMUSG00225031984
 protein coding gene Chr16:16212902-16244662 (+)
PWK/PhJ ENSLUMG00010044025
 protein coding gene Chr16:10378093-10409374 (+)
SPRET/EiJ ENSMSPG00010042470
 protein coding gene Chr16:10350316-10380792 (+)
WSB/EiJ ENSIUOG00005033928
 protein coding gene Chr16:10465652-10497174 (+)



Homology
more
  • Human Ortholog
    BFAR, bifunctional apoptosis regulator
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BFAR, bifunctional apoptosis regulator
  • Synonyms
    BAR, RNF47
  • Links
    NCBI Gene ID: 51283
    UniProt: Q9NZS9

  • Chr Location
    16p13.12; chr16:14632830-14669237 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    667
  • Tissues
    57
  • cDNA Data
    10
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67118 NCBI Gene Model | MGI Sequence Detail 31755 C57BL/6J ±  kb
transcript NM_025976 RefSeq | MGI Sequence Detail 3010 C57BL/6  
polypeptide Q8R079 UniProt | EBI | MGI Sequence Detail 450 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2146480, MGI:2146617
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:358003 Das A, et al., The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2312291121
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory