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Bfar Gene Detail
Summary
  • Symbol
    Bfar
  • Name
    bifunctional apoptosis regulator
  • Synonyms
    3010001A07Rik, RNF47
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914368
    NCBI Gene: 67118
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:13671858-13703612 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 9.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914368
protein coding gene Chr16:13671858-13703612 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022532
protein coding gene Chr16:10652095-10683301 (+)
A/J MGP_AJ_G0022494
protein coding gene Chr16:10070243-10102011 (+)
AKR/J MGP_AKRJ_G0022470
protein coding gene Chr16:10507267-10538521 (+)
BALB/cJ MGP_BALBcJ_G0022498
protein coding gene Chr16:10234622-10269640 (+)
C3H/HeJ MGP_C3HHeJ_G0022265
protein coding gene Chr16:10600495-10633631 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022947
protein coding gene Chr16:10819327-10850485 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020467
protein coding gene Chr16:10164606-10195407 (+)
CAST/EiJ MGP_CASTEiJ_G0021792
protein coding gene Chr16:10606124-10639487 (+)
CBA/J MGP_CBAJ_G0022234
protein coding gene Chr16:11307574-11338787 (+)
DBA/2J MGP_DBA2J_G0022365
protein coding gene Chr16:10068227-10100355 (+)
FVB/NJ MGP_FVBNJ_G0022341
protein coding gene Chr16:10052164-10084148 (+)
LP/J MGP_LPJ_G0022433
protein coding gene Chr16:10567795-10598797 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022363
protein coding gene Chr16:10963758-10994885 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022960
protein coding gene Chr16:10484576-10516984 (+)
PWK/PhJ MGP_PWKPhJ_G0021534
protein coding gene Chr16:10326166-10359577 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021362
protein coding gene Chr16:10466881-10503940 (+)
WSB/EiJ MGP_WSBEiJ_G0021840
protein coding gene Chr16:10495302-10527780 (+)



Homology
more
  • Human Ortholog
    BFAR, bifunctional apoptosis regulator
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BFAR, bifunctional apoptosis regulator
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAR, RNF47
  • Links
    NCBI Gene ID: 51283
    neXtProt AC: NX_Q9NZS9
    UniProt: Q9NZS9

  • Chr Location
    16p13.12; chr16:14632811-14669236 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9563
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BFAR
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67118 NCBI Gene Model | MGI Sequence Detail 31755 C57BL/6J ±  kb
transcript NM_025976 RefSeq | MGI Sequence Detail 3010 C57BL/6  
polypeptide NP_080252 RefSeq | MGI Sequence Detail 450 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146480, MGI:2146617
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory