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Trak1
Gene Detail
 Symbol
Name
ID
Trak1
trafficking protein, kinesin binding 1
MGI:1914345
Synonyms 2310001H13Rik, hyrt, nm1952
Feature Type protein coding gene
Genetic Map
Chromosome 9
72.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:121366958-121474916 bp, + strand
From Ensembl annotation of GRCm38

  107959 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:25103  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken

Gene Tree: Trak1

Human
homologs
Human Homolog TRAK1, trafficking protein, kinesin binding 1
NCBI Gene ID 22906
neXtProt AC  NX_Q9UPV9
Human Synonyms  MILT1, OIP106
Human Chr (Location)  3p22.1; chr3:42013802-42225890 (+)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(5) Spontaneous(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice with a spontaneous mutation in this allele have various behavioral abnormalities consistent with hypertonia. Inclusions can be found in neuronal processes of the gray matter of the brainstem and spinal cord.
 
Human Diseases Modeled Using Mouse Trak1 (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process endosome to lysosome transport
Component cytoplasm, early endosome, ...
Function GABA receptor binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (89)    Tissues (12)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 89
cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000032536 (Evidence)
Entrez Gene67095 (Evidence)
DFCITC1574644, TC1585045, TC1596693, TC1641504
DoTSDT.101378947, DT.101378955, DT.487818, DT.55100590, DT.91383605, DT.94259067, DT.97400447
NIA Mouse Gene IndexU011163
Consensus CDS ProjectCCDS40810.1
International Mouse Knockout Project StatusTrak1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032536 Ensembl Gene Model | MGI Sequence Detail 107959 C57BL/6J ±  kb
transcript ENSMUST00000045903 Ensembl | MGI Sequence Detail 4883 Not Applicable 
polypeptide ENSMUSP00000044482 Ensembl | MGI Sequence Detail 939 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(35) UniProt(6)
Polymorphisms SNPs within 2kb(778 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006933 HAP1, N-terminal
InterPro IPR022154 Trafficking kinesin-binding protein domain
Protein Ontology PR:000016607 trafficking kinesin-binding protein 1
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:197848 van Spronsen M, et al., TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron. 2013 Feb 6;77(3):485-502
All references(35)
Other
accession IDs
MGI:2143032, MGI:2143074, MGI:3044766

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory