Trak1
Gene Detail

Symbol Name ID

Trak1 trafficking protein, kinesin binding 1 MGI:1914345

Synonyms

2310001H13Rik, hyrt, nm1952

Feature Type

protein coding gene

Genetic Map

Chromosome 9

72.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:121366958-121474916 bp, + strand From Ensembl annotation of GRCm38   107959 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:25103  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Trak1

Human homologs

Human Homolog		TRAK1, trafficking protein, kinesin binding 1
NCBI Gene ID		22906
neXtProt AC		NX_Q9UPV9
Human Synonyms		MILT1, OIP106
Human Chr (Location)		3p22.1; chr3:42132746-42267382 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Gene trapped(5) Spontaneous(1)
 

Mice with a spontaneous mutation in this allele have various behavioral abnormalities consistent with hypertonia. Inclusions can be found in neuronal processes of the gray matter of the brainstem and spinal cord.

 
Human Diseases Modeled Using Mouse Trak1 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	endosome to lysosome transport
Component	cytoplasm, early endosome, ...
Function	GABA receptor binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (89)    Tissues (12)    Images (23)
Theiler Stages: 23

Assay Type	Results
RNA in situ	89

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(16)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000032536 (Evidence)
Entrez Gene	67095 (Evidence)
DFCI	TC1574644, TC1585045, TC1596693, TC1641504
DoTS	DT.101378947, DT.101378955, DT.487818, DT.55100590, DT.91383605, DT.94259067, DT.97400447
NIA Mouse Gene Index	U011163
Consensus CDS Project	CCDS40810.1
International Mouse Knockout Project Status	Trak1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000032536	Ensembl Gene Model | MGI Sequence Detail	107959	C57BL/6J
transcript	ENSMUST00000045903	Ensembl | MGI Sequence Detail	4883	Not Applicable
polypeptide	ENSMUSP00000044482	Ensembl | MGI Sequence Detail	939	Not Applicable

All sequences(46) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(662 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006933	HAP1, N-terminal
InterPro	IPR022154	Trafficking kinesin-binding protein domain
Protein Ontology	PR:000016607	trafficking kinesin-binding protein 1

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)

Other accession IDs

MGI:2143032, MGI:2143074, MGI:3044766