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Trappc6a Gene Detail
Summary
  • Symbol
    Trappc6a
  • Name
    trafficking protein particle complex 6A
  • Synonyms
    1810073E21Rik, 4930519D19Rik, TRS33
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914341
    NCBI Gene: 67091
Location & Maps
more
  • Sequence Map
    Chr7:19508395-19516145 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7751 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.92 cM, cytoband A2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TRAPPC6A, trafficking protein particle complex 6A
  • Vertebrate Orthologs
    6
  • Human Ortholog
    TRAPPC6A, trafficking protein particle complex 6A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TRS33
  • Links
    NCBI Gene ID: 79090
    neXtProt AC: NX_O75865
    UniProt: O75865

  • Chr Location
    19q13.32; chr19:45162928-45178302 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice exhibit pigmentation abnormalities including mosaic loss of coat pigment, patchy loss of pigmentation in the retinal pigmented epithelial layer, and abnormal melanosomes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022255 VEGA Gene Model | MGI Sequence Detail 7751 C57BL/6J ±  kb
transcript OTTMUST00000052966 VEGA | MGI Sequence Detail 651 Not Applicable  
polypeptide OTTMUSP00000025166 VEGA | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    36 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016617 trafficking protein particle complex subunit 6A
  • InterPro Domains
    IPR024096 NO signalling/Golgi transport ligand-binding domain
    IPR007194 Transport protein particle (TRAPP) component
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 5
Other
Accession IDs
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MGI:1922355, MGI:2141982, MGI:3577867
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:14372 Matthews RJ, et al., Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4444-8
  • Latest
    J:238174 Chang JY, et al., Trafficking protein particle complex 6A delta (TRAPPC6ADelta) is an extracellular plaque-forming protein in the brain. Oncotarget. 2015 Feb 28;6(6):3578-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory