About   Help   FAQ
Psmc6 Gene Detail
Summary
  • Symbol
    Psmc6
  • Name
    proteasome (prosome, macropain) 26S subunit, ATPase, 6
  • Synonyms
    2300001E01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914339
    NCBI Gene: 67089
  • Gene Overview
    MyGene.info: PSMC6
Location & Maps
more
  • Sequence Map
    Chr14:45329824-45349071 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19248 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 22.89 cM, cytoband C1
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PSMC6, proteasome 26S subunit, ATPase 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMC6, proteasome 26S subunit, ATPase 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CADP44, HEL-S-73, p42, P44, SUG2
  • Links
    NCBI Gene ID: 5706
    neXtProt AC: NX_P62333

  • Chr Location
    14q22.1; chr14:52707163-52727998 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Targeted
    3
  • Genomic Mutations
    1 involving Psmc6
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67089 NCBI Gene Model | MGI Sequence Detail 19248 C57BL/6J ±  kb
transcript NM_025959 RefSeq | MGI Sequence Detail 1564 C57BL/6  
polypeptide P62334 UniProt | EBI | MGI Sequence Detail 389 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013384 26S protease regulatory subunit S10B
  • InterPro Domains
    IPR005937 26S proteasome subunit P45
    IPR003593 AAA+ ATPase domain
    IPR003960 ATPase, AAA-type, conserved site
    IPR003959 ATPase, AAA-type, core
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 176
    cDNA 176

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145653
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228828 Hamazaki J, et al., Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015 Jul;11(7):e1005401

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/24/2016
MGI 6.04
The Jackson Laboratory