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Magt1 Gene Detail
Summary
  • Symbol
    Magt1
  • Name
    magnesium transporter 1
  • Synonyms
    2410001C15Rik, 2610529C04Rik, 2810482I07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914325
    NCBI Gene: 67075
  • Gene Overview
    MyGene.info: MAGT1
Location & Maps
more
  • Sequence Map
    ChrX:105968084-106011906 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      43823 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MAGT1, magnesium transporter 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MAGT1, magnesium transporter 1
    Orthology source: HomoloGene
  • Synonyms
    bA217H1.1, IAP, MRX95, OST3B, PRO0756, XMEN
  • Links
    NCBI Gene ID: 84061
    neXtProt AC: NX_Q9H0U3

  • Chr Location
    Xq21.1; chrX:77826364-77895568 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human MAGT1 associations

Human Disease Mouse Models
       Immunodeficiency, X-Linked, with Magnesium Defect, Epstein-Barr Virus Infection, and Neoplasia; XMEN   OMIM: 300853
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    33
  • Gene trapped
    31
  • Targeted
    2
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018276 VEGA Gene Model | MGI Sequence Detail 43823 C57BL/6J ±  kb
transcript OTTMUST00000044163 VEGA | MGI Sequence Detail 4531 Not Applicable  
polypeptide OTTMUSP00000019852 VEGA | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    155 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010088 magnesium transporter protein 1
  • InterPro Domains
    IPR006844 Magnesium transporter protein 1
    IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
    IPR013766 Thioredoxin domain
    IPR012336 Thioredoxin-like fold
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
Other
Accession IDs
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MGI:1914493, MGI:1917001
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:181586 Hald J, et al., Pancreatic islet and progenitor cell surface markers with cell sorting potential. Diabetologia. 2012 Jan;55(1):154-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory