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Dynlrb1
Gene Detail
Symbol

Name
ID
Dynlrb1
dynein light chain roadblock-type 1
MGI:1914318
Synonyms
2010012N15Rik, 2010320M17Rik, Dncl2a, DNLC2A, km23-1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
77.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:155236533-155250277 bp, + strand
From VEGA annotation of GRCm38

  13745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69161  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DYNLRB1
Protein SuperFamily: cytoplasmic dynein light chain, LC7 type
Gene Tree: Dynlrb1

Human
homologs
DYNLRB1, dynein, light chain, roadblock-type 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 83658
neXtProt AC: NX_Q9NP97

Human Synonyms: BITH, BLP, DNCL2A, DNLC2A, ROBLD1

Human Chr (Location): 20q11.21; chr20:34516355-34540958 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(19) Targeted(2)
Interactions
Dynlrb1 interacts with 38 markers (Mir1a-1, Mir1a-2, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process transport, visual behavior
Component centrosome, cytoplasm, ...
Function identical protein binding, motor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (34)    Tissues (29)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 34
cDNA source data(179)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dynlrb1 ; ZFIN dynlrb1    NEW 
Molecular
reagents
All nucleic(179) cDNA(179)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000016009 (Evidence)
Ensembl Gene Model ENSMUSG00000047459 (Evidence)
Entrez Gene 67068 (Evidence)
UniGene 23693
DFCI TC1686508, TC1572460
DoTS DT.101369176, DT.94399166, DT.94399108, DT.495972, DT.97377228
NIA Mouse Gene Index U002700
PDB 1Y4O
Consensus CDS Project CCDS38294.1, CCDS71166.1
International Mouse Phenotyping Consortium Status Dynlrb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016009 VEGA Gene Model | MGI Sequence Detail 13745 C57BL/6J ±  kb
transcript OTTMUST00000038126 VEGA | MGI Sequence Detail 788 Not Applicable 
polypeptide OTTMUSP00000017094 VEGA | MGI Sequence Detail 104 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004942 Dynein light chain-related
InterPro IPR016561 Dynein light chain, roadblock-type
Protein Ontology PR:000006777 dynein light chain roadblock-type 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:210222 Hupe M, et al., Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Nucleic Acids Res. 2014 Jan;42(2):e14
All references(39)
Other
accession IDs
MGI:1917123, MGI:2139256

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory