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Yaf2 Gene Detail
Summary
  • Symbol
    Yaf2
  • Name
    YY1 associated factor 2
  • Synonyms
    2810021M11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914307
    NCBI Gene: 67057
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:93182159-93234816 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 47.39 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1441 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914307
 protein coding gene Chr15:93181714-93234816 (-)
129S1/SvImJ ENSMUSG00200033227
 protein coding gene Chr15:90321623-90374336 (-)
A/J ENSMUSG00195017268
 protein coding gene Chr15:90218858-90271593 (-)
AKR/J ENSMUSG00220026587
 protein coding gene Chr15:90274726-90327386 (-)
BALB/cJ ENSMUSG00180013936
 protein coding gene Chr15:90110436-90163108 (-)
C3H/HeJ ENSMUSG00175026031
 protein coding gene Chr15:90405261-90457974 (-)
C57BL/6NJ ENSMUSG00215027842
 protein coding gene Chr15:90218695-90271360 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020190
 protein coding gene Chr15:87071251-87127432 (-)
CAST/EiJ ENSTCUG00005028583
 protein coding gene Chr15:89711480-89764886 (-)
CBA/J ENSMUSG00210012995
 protein coding gene Chr15:90186674-90239388 (-)
DBA/2J ENSMUSG00185022297
 protein coding gene Chr15:90234826-90287539 (-)
FVB/NJ ENSMUSG00205024372
 protein coding gene Chr15:89939318-89992044 (-)
JF1/MsJ ENSUMUG00000040965
 protein coding gene Chr15:89736089-89798688 (-)
LP/J ENSMUSG00230032407
 protein coding gene Chr15:93559605-93612320 (-)
NOD/ShiLtJ ENSMUSG00190024791
 protein coding gene Chr15:90228774-90281491 (-)
NZO/HlLtJ ENSMUSG00225042767
 protein coding gene Chr15:93858117-93910818 (-)
PWK/PhJ ENSLUMG00010028960
 protein coding gene Chr15:89886765-89939483 (-)
SPRET/EiJ ENSMSPG00010013433
 protein coding gene Chr15:91700502-91752757 (-)
WSB/EiJ ENSIUOG00005010765
 protein coding gene Chr15:90323994-90376671 (-)



Homology
more
  • Human Ortholog
    YAF2, YY1 associated factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    YAF2, YY1 associated factor 2
  • Links
    NCBI Gene ID: 10138
    UniProt: Q8IY57

  • Chr Location
    12q12; chr12:42157104-42238349 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    68
  • cDNA Data
    57
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022634 Ensembl Gene Model | MGI Sequence Detail 52658 C57BL/6J ±  kb
transcript ENSMUST00000080299 Ensembl | MGI Sequence Detail 1676 Not Applicable  
polypeptide ENSMUSP00000079179 Ensembl | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 57
    Primer pair 2
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 71
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 9
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory