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Rars
Gene Detail
Symbol

Name
ID
Rars
arginyl-tRNA synthetase
MGI:1914297
Synonyms
2610011N19Rik, 2610037E21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
21.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:35808381-35834506 bp, - strand
From VEGA annotation of GRCm38

  26126 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68281  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RARS
Gene Tree: Rars

Human
homologs
RARS, arginyl-tRNA synthetase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5917
neXtProt AC: NX_P54136

Human Synonyms: ArgRS, DALRD1, HLD9

Human Chr (Location): 5q35.1; chr5:168486458-168519306 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RARS

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rars interacts with 46 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process arginyl-tRNA aminoacylation, translation, ...
Component aminoacyl-tRNA synthetase multienzyme complex, cytoplasm, ...
Function aminoacyl-tRNA ligase activity, arginine binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (188)    Tissues (95)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 188
cDNA source data(248)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rars    NEW 
Molecular
reagents
All nucleic(250) cDNA(248) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000005415 (Evidence)
Ensembl Gene Model ENSMUSG00000018848 (Evidence)
Entrez Gene 104458 (Evidence)
UniGene 284906
DFCI TC1572137, TC1602974
DoTS DT.494786, DT.94261704
EC 6.1.1.19
Consensus CDS Project CCDS24544.1
International Mouse Phenotyping Consortium Status Rars
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005415 VEGA Gene Model | MGI Sequence Detail 26126 C57BL/6J ±  kb
transcript OTTMUST00000012068 VEGA | MGI Sequence Detail 2109 Not Applicable 
polypeptide OTTMUSP00000005592 VEGA | MGI Sequence Detail 660 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(175 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
InterPro IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site
InterPro IPR001278 Arginine-tRNA ligase
InterPro IPR005148 Arginyl tRNA synthetase N-terminal domain
InterPro IPR008909 DALR anticodon binding
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000013742 arginyl-tRNA synthetase, cytoplasmic
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:1924077, MGI:2144362, MGI:2144591

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory