About   Help   FAQ
Tbc1d7
Gene Detail
 Symbol
Name
ID
Tbc1d7
TBC1 domain family, member 7
MGI:1914296
Synonyms 2610009C09Rik
Feature Type protein coding gene
Genetic Map
Chromosome 13
21.31 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:43151744-43171501 bp, - strand
From Ensembl annotation of GRCm38

  19758 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9538  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tbc1d7

Human
homologs
Human Homolog TBC1D7, TBC1 domain family, member 7
NCBI Gene ID 51256
neXtProt AC  NX_Q9P0N9
Human Synonyms  MGCPH, PIG51, TBC7
Human Chr (Location)  6p24.1; chr6:13304951-13328583 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TBC1D7
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tbc1d7 interacts with 23 markers (Mir29a, Mir29b-1, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process activation of Rho GTPase activity, negative regulation of cilium assembly, ...
Component ciliary basal body, cytoplasmic vesicle
Function GTPase activator activity, Rab GTPase activator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (38)    Tissues (6)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 38
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000021368 (Evidence)
Entrez Gene67046 (Evidence)
DFCITC1579651, TC1587085, TC1689292
DoTSDT.60118421, DT.94344517, DT.94371059
NIA Mouse Gene IndexU034720
Consensus CDS ProjectCCDS26476.1
International Mouse Knockout Project StatusTbc1d7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021368 Ensembl Gene Model | MGI Sequence Detail 19758 C57BL/6J ±  kb
transcript ENSMUST00000179852 Ensembl | MGI Sequence Detail 1259 Not Applicable 
polypeptide ENSMUSP00000137280 Ensembl | MGI Sequence Detail 293 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(222 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000195 Rab-GTPase-TBC domain
Protein Ontology PR:000016120 TBC1 domain family member 7
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187614 Dibble CC, et al., TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1. Mol Cell. 2012 Aug 24;47(4):535-46
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory