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Tbc1d7 Gene Detail
Summary
  • Symbol
    Tbc1d7
  • Name
    TBC1 domain family, member 7
  • Synonyms
    2610009C09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914296
    NCBI Gene: 67046
Location & Maps
more
  • Sequence Map
    Chr13:43151744-43171501 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19758 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TBC1D7, TBC1 domain family member 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TBC1D7, TBC1 domain family member 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MGCPH, PIG51, TBC7
  • Links
    NCBI Gene ID: 51256
    neXtProt AC: NX_Q9P0N9

  • Chr Location
    6p24.1; chr6:13304951-13328583 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9538
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TBC1D7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    2
  • Genomic Mutations
    1 involving Tbc1d7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021368 Ensembl Gene Model | MGI Sequence Detail 19758 C57BL/6J ±  kb
transcript ENSMUST00000179852 Ensembl | MGI Sequence Detail 1259 Not Applicable  
polypeptide ENSMUSP00000137280 Ensembl | MGI Sequence Detail 293 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    222 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000016120 TBC1 domain family member 7
  • InterPro Domains
    IPR000195 Rab-GTPase-TBC domain
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187614 Dibble CC, et al., TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1. Mol Cell. 2012 Aug 24;47(4):535-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory