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Higd2a Gene Detail
Summary
  • Symbol
    Higd2a
  • Name
    HIG1 domain family, member 2A
  • Synonyms
    2010110M21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914294
    NCBI Gene: 67044
Location & Maps
more
  • Sequence Map
    Chr13:54590207-54591158 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      952 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 28.84 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HIGD2A, HIG1 hypoxia inducible domain family member 2A
  • Vertebrate Orthologs
    11
  • Human Ortholog
    HIGD2A, HIG1 hypoxia inducible domain family member 2A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RCF1b
  • Links
    NCBI Gene ID: 192286
    neXtProt AC: NX_Q9BW72

  • Chr Location
    5q35.2; chr5:176388783-176389750 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Higd2a
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032685 VEGA Gene Model | MGI Sequence Detail 952 C57BL/6J ±  kb
transcript OTTMUST00000081337 VEGA | MGI Sequence Detail 648 Not Applicable  
polypeptide OTTMUSP00000043496 VEGA | MGI Sequence Detail 106 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    27 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029544 HIG1 domain family member 2A
  • InterPro Domains
    IPR007667 Hypoxia induced protein, domain
Molecular
Reagents
less
  • All nucleic 117
    cDNA 117

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145173
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:182674 Chen YC, et al., Identification of a protein mediating respiratory supercomplex stability. Cell Metab. 2012 Mar 7;15(3):348-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory