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Ift27
Gene Detail
 Symbol
Name
ID
Ift27
intraflagellar transport 27
MGI:1914292
Synonyms 2600013G09Rik, Rabl4
Feature Type protein coding gene
Genetic Map
Chromosome 15
36.92 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:78159465-78174108 bp, - strand
From Ensembl annotation of GRCm38

  14644 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4998  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Ift27

Human
homologs
Human Homolog IFT27, intraflagellar transport 27
NCBI Gene ID 11020
neXtProt AC  NX_Q9BW83
Human Synonyms  BBS19, RABL4, RAYL
Human Chr (Location)  22q13.1; chr22:36758202-36776133 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human IFT27
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Radiation induced(1) Targeted(6)
Genomic Mutations involving Ift27 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ift27 interacts with 24 markers (Mir129-1, Mir129-2, Mir188, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process intraciliary transport, small GTPase mediated signal transduction
Component cell, cell projection, ...
Function GTP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(60)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) cDNA(60)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000016637 (Evidence)
Entrez Gene67042 (Evidence)
UniGene30191
DFCITC1577648, TC1612781
DoTSDT.493915, DT.91340931
NIA Mouse Gene IndexU036377
Consensus CDS ProjectCCDS37131.1
International Mouse Knockout Project StatusIft27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016637 Ensembl Gene Model | MGI Sequence Detail 14644 C57BL/6J ±  kb
transcript ENSMUST00000016781 Ensembl | MGI Sequence Detail 1012 Not Applicable 
polypeptide ENSMUSP00000016781 Ensembl | MGI Sequence Detail 186 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(173 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000029557 intraflagellar transport protein 27 homolog
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203626 Howard PW, et al., Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17. Exp Cell Res. 2013 Aug 15;319(14):2275-81
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory