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Ift27
Gene Detail
Symbol

Name
ID
Ift27
intraflagellar transport 27
MGI:1914292
Synonyms
2600013G09Rik, Rabl4
Feature Type
protein coding gene
Genetic Map
Chromosome 15
36.92 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:78159465-78174108 bp, - strand
From Ensembl annotation of GRCm38

  14644 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4998  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IFT27
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Ift27

Human
homologs
IFT27, intraflagellar transport 27
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 11020
neXtProt AC: NX_Q9BW83

Human Synonyms: BBS19, RABL4, RAYL

Human Chr (Location): 22q13.1; chr22:36758202-36776133 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human IFT27

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Radiation induced(1) Targeted(9)
Genomic Mutations involving Ift27 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Ift27 interacts with 24 markers (Mir129-1, Mir129-2, Mir188, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process intracellular protein transport, intraciliary transport, ...
Component cell, cell projection, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(60)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ift27 ; ZFIN ift27    NEW 
Molecular
reagents
All nucleic(60) cDNA(60)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000016637 (Evidence)
Entrez Gene 67042 (Evidence)
UniGene 30191
DFCI TC1612781, TC1577648
DoTS DT.493915, DT.91340931
NIA Mouse Gene Index U036377
Consensus CDS Project CCDS37131.1
International Mouse Phenotyping Consortium Status Ift27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016637 Ensembl Gene Model | MGI Sequence Detail 14644 C57BL/6J ±  kb
transcript ENSMUST00000016781 Ensembl | MGI Sequence Detail 1012 Not Applicable 
polypeptide ENSMUSP00000016781 Ensembl | MGI Sequence Detail 186 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(173 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000029557 intraflagellar transport protein 27 homolog
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:217667 May-Simera HL, et al., Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. Development. 2015 Feb 1;142(3):555-66
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory