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Rpl11 Gene Detail
Summary
  • Symbol
    Rpl11
  • Name
    ribosomal protein L11
  • Synonyms
    2010203J19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914275
    NCBI Gene: 67025
Location & Maps
more
  • Sequence Map
    Chr4:136028265-136053428 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25164 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RPL11, ribosomal protein L11
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RPL11, ribosomal protein L11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DBA7, GIG34, L11
  • Links
    NCBI Gene ID: 6135
    neXtProt AC: NX_P62913

  • Chr Location
    1p36.1-p35; chr1:23691779-23696425 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human RPL11 associations

Human Disease Mouse Models
       Diamond-Blackfan Anemia 7; DBA7   OMIM: 612562
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    2
  • Gene trapped
    13
  • Targeted
    2
  • Genomic Mutations
    3 involving Rpl11
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009855 VEGA Gene Model | MGI Sequence Detail 25164 C57BL/6J ±  kb
transcript OTTMUST00000022846 VEGA | MGI Sequence Detail 833 Not Applicable  
polypeptide OTTMUSP00000010420 VEGA | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    301 from dbSNP Build 137
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR002132 Ribosomal protein L5
    IPR020929 Ribosomal protein L5, conserved site
    IPR031309 Ribosomal protein L5, C-terminal
    IPR022803 Ribosomal protein L5 domain
    IPR031310 Ribosomal protein L5, N-terminal
Molecular
Reagents
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  • All nucleic 16
    cDNA 16

    Microarray probesets 8
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194321 Nott A, et al., S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3113-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory