Acad9 MGI Mouse Gene Detail - MGI:1914272 - acyl-Coenzyme A dehydrogenase family, member 9

Symbol

Acad9
Name

acyl-Coenzyme A dehydrogenase family, member 9
Synonyms

2600017P15Rik, C630012L17Rik, NPD002

Feature Type

protein coding gene
IDs

MGI:1914272
NCBI Gene: 229211
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr3:36120128-36147002 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 17.41 cM, cytoband B
Mapping Data

2 experiments

SNPs within 2kb

178 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914272	protein coding gene	Chr3:36120128-36147006 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027155	protein coding gene	Chr3:33832233-33859412 (+)
A/J	MGP_AJ_G0027115	protein coding gene	Chr3:33201922-33234386 (+)
AKR/J	MGP_AKRJ_G0027084	protein coding gene	Chr3:33806340-33834597 (+)
BALB/cJ	MGP_BALBcJ_G0027127	protein coding gene	Chr3:32961939-32989522 (+)
C3H/HeJ	MGP_C3HHeJ_G0026870	protein coding gene	Chr3:33875127-33903858 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027573	protein coding gene	Chr3:35462946-35495410 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0024934	protein coding gene	Chr3:30925667-30949748 (+)
CAST/EiJ	MGP_CASTEiJ_G0026323	protein coding gene	Chr3:33717202-33745684 (+)
CBA/J	MGP_CBAJ_G0026847	protein coding gene	Chr3:36404592-36438731 (+)
DBA/2J	MGP_DBA2J_G0026981	protein coding gene	Chr3:32668300-32695162 (+)
FVB/NJ	MGP_FVBNJ_G0026949	protein coding gene	Chr3:32125055-32152729 (+)
LP/J	MGP_LPJ_G0027093	protein coding gene	Chr3:34606401-34634628 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0026969	protein coding gene	Chr3:38859436-38886704 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027632	protein coding gene	Chr3:33655983-33687828 (+)
PWK/PhJ	MGP_PWKPhJ_G0026056	protein coding gene	Chr3:32320903-32347368 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0025868	protein coding gene	Chr3:33028912-33058219 (+)
WSB/EiJ	MGP_WSBEiJ_G0026397	protein coding gene	Chr3:33680145-33706997 (+)

Human Ortholog

ACAD9, acyl-CoA dehydrogenase family member 9

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ACAD9, acyl-CoA dehydrogenase family member 9
Synonyms

MC1DN20, NPD002
Links

HGNC:21497

NCBI Gene ID: 28976

neXtProt AC: NX_Q9H845

UniProt: Q9H845
Chr Location

3q21.3; chr3:128879490-128916075 (+) GRCh38.p7

Alliance of Genome Resources

Acad9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ACAD9
Gene Tree

Acad9

Diseases

1 with human ACAD9 associations

				Human Disease	Mouse Models
				nuclear type mitochondrial complex I deficiency 20 IDs nuclear type mitochondrial complex I deficiency 20 DOID:0112072 MESH:C567006 OMIM:611126 ORDO:99901 UMLS_CUI:C1970173

Click on a disease name to see all genes associated with that disease.

References

1 with disease annotations

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

10
Endonuclease-mediated

4
Gene trapped

1
Radiation induced

1
Targeted

4
Genomic Mutations

1 involving Acad9
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

28 strains or lines available

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All GO Annotations

19
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

769
Tissues

97
cDNA Data

122
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase acad9

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Acad9 interacts with 342 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

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All Sequences

84
RefSeq

5
UniProt

5
CCDS

CCDS17310.1

Ensembl

ENSMUSG00000027710 (Evidence)
NCBI Gene

229211

			Length	Strain/Species	Flank
genomic	ENSMUSG00000027710	Ensembl Gene Model \| MGI Sequence Detail	26875	C57BL/6J	± kb
transcript	ENSMUST00000011492	Ensembl \| MGI Sequence Detail	3930	Not Applicable
polypeptide	ENSMUSP00000011492	Ensembl \| MGI Sequence Detail	625	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000003599 complex I assembly factor ACAD9, mitochondrial

(term hierarchy)
EC

1.3.8.-
InterPro Domains

IPR006089 Acyl-CoA dehydrogenase, conserved site

IPR036250 Acyl-CoA dehydrogenase-like, C-terminal

IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal

IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal

IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily

IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily

IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain

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All nucleic 124

cDNA 122

Primer pair 1

Other 1

Microarray probesets 7

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MGI:2444674

Summaries

All 36

Developmental Gene Expression 2

Diseases 1

Gene Ontology 6

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Acad9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr28859	Chr3:36120133-36120153 (+)	15 bp
Tssr28860	Chr3:36120195-36120212 (+)	76 bp
Tssr28861	Chr3:36120213-36120251 (+)	104 bp
Tssr28862	Chr3:36120260-36120267 (+)	136 bp
Tssr28863	Chr3:36130061-36130064 (+)	9,935 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 07/26/2022 MGI 6.21