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Tmem88 Gene Detail
Summary
  • Symbol
    Tmem88
  • Name
    transmembrane protein 88
  • Synonyms
    2600017H02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914270
    NCBI Gene: 67020
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69396519-69398234 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.60 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914270
protein coding gene Chr11:69396516-69398234 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018533
protein coding gene Chr11:69825099-69826813 (-)
A/J MGP_AJ_G0018501
protein coding gene Chr11:67198050-67199764 (-)
AKR/J MGP_AKRJ_G0018470
protein coding gene Chr11:69208222-69209936 (-)
BALB/cJ MGP_BALBcJ_G0018473
protein coding gene Chr11:67517051-67518765 (-)
C3H/HeJ MGP_C3HHeJ_G0018286
protein coding gene Chr11:69226523-69228237 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018924
protein coding gene Chr11:71939030-71940745 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016569
protein coding gene Chr11:64126911-64128625 (-)
CAST/EiJ MGP_CASTEiJ_G0017841
protein coding gene Chr11:69462480-69464194 (-)
CBA/J MGP_CBAJ_G0018259
protein coding gene Chr11:75161314-75163028 (-)
DBA/2J MGP_DBA2J_G0018368
protein coding gene Chr11:66788978-66790689 (-)
FVB/NJ MGP_FVBNJ_G0018358
protein coding gene Chr11:66415908-66417622 (-)
LP/J MGP_LPJ_G0018438
protein coding gene Chr11:70395210-70396924 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018381
protein coding gene Chr11:75774112-75775826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018966
protein coding gene Chr11:69457417-69459131 (-)
PWK/PhJ MGP_PWKPhJ_G0017615
protein coding gene Chr11:67432095-67433806 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017405
protein coding gene Chr11:69279382-69281089 (-)
WSB/EiJ MGP_WSBEiJ_G0017895
protein coding gene Chr11:69136579-69138293 (-)



Homology
more
  • Human Ortholog
    TMEM88, transmembrane protein 88
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM88, transmembrane protein 88
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 92162
    neXtProt AC: NX_Q6PEY1
    UniProt: Q6PEY1

  • Chr Location
    17p13.1; chr17:7854886-7856099 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045377 Ensembl Gene Model | MGI Sequence Detail 1716 C57BL/6J ±  kb
transcript ENSMUST00000050140 Ensembl | MGI Sequence Detail 1582 Not Applicable  
polypeptide ENSMUSP00000055528 Ensembl | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:236978 Santos R, et al., Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects. PLoS Biol. 2016 Sep;14(9):e2000197

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory