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Tbc1d2b
Gene Detail
Symbol

Name
ID
Tbc1d2b
TBC1 domain family, member 2B
MGI:1914266
Synonyms
1810061M12Rik, mKIAA1055
Feature Type
protein coding gene
Genetic Map
Chromosome 9
47.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:90202027-90270804 bp, - strand
From VEGA annotation of GRCm38

  68778 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56694  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TBC1D2B
Gene Tree: Tbc1d2b

Human
homologs
TBC1D2B, TBC1 domain family, member 2B
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23102
neXtProt AC: NX_Q9UPU7

Human Chr (Location): 15q24.3-q25.1; chr15:77994985-78077667 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Tbc1d2b interacts with 319 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function GTPase activator activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (118)    Tissues (109)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tbc1d2b    NEW 
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000031688 (Evidence)
Ensembl Gene Model ENSMUSG00000037410 (Evidence)
Entrez Gene 67016 (Evidence)
DFCI TC1738570, TC1664948, TC1655851, TC1601825
DoTS DT.97412692, DT.94295043, DT.491529, DT.40185168
NIA Mouse Gene Index U031178
Consensus CDS Project CCDS23401.1
International Mouse Phenotyping Consortium Status Tbc1d2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031688 VEGA Gene Model | MGI Sequence Detail 68778 C57BL/6J ±  kb
transcript OTTMUST00000078503 VEGA | MGI Sequence Detail 5956 Not Applicable 
polypeptide OTTMUSP00000041747 VEGA | MGI Sequence Detail 965 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(5) UniProt(4)
Polymorphisms
SNPs within 2kb(476 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR000195 Rab-GTPase-TBC domain
Protein Ontology PR:000016111 TBC1 domain family member 2B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)
Other
accession IDs
MGI:2143080, MGI:2143251, MGI:2143252, MGI:2143307

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory