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Uqcrc2 Gene Detail
Summary
  • Symbol
    Uqcrc2
  • Name
    ubiquinol cytochrome c reductase core protein 2
  • Synonyms
    1500004O06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914253
    NCBI Gene: 67003
  • Gene Overview
    MyGene.info: UQCRC2
Location & Maps
more
  • Sequence Map
    Chr7:120635176-120659524 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24349 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 64.90 cM, cytoband F3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    UQCRC2, ubiquinol-cytochrome c reductase core protein II
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UQCRC2, ubiquinol-cytochrome c reductase core protein II
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MC3DN5, QCR2, UQCR2
  • Links
    NCBI Gene ID: 7385
    neXtProt AC: NX_P22695

  • Chr Location
    16p12.2; chr16:21953288-21983347 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37764
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: UQCRC2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human UQCRC2 associations

Human Disease Mouse Models
       Mitochondrial Complex III Deficiency, Nuclear Type 5; MC3DN5   OMIM: 615160
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    5
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025574 VEGA Gene Model | MGI Sequence Detail 24349 C57BL/6J ±  kb
transcript OTTMUST00000062904 VEGA | MGI Sequence Detail 1896 Not Applicable  
polypeptide OTTMUSP00000031073 VEGA | MGI Sequence Detail 453 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    172 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 410
    cDNA 409
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 6
    Gene Ontology 13
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:236011 Odegaard JI, et al., Perinatal Licensing of Thermogenesis by IL-33 and ST2. Cell. 2016 Aug 11;166(4):841-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory