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Prl3a1 Gene Detail
Summary
  • Symbol
    Prl3a1
  • Name
    prolactin family 3, subfamily a, member 1
  • Synonyms
    1600016E11Rik, PLP-H, Plpi, PLP-I, Prlpi
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914250
    NCBI Gene: 67000
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27443472-27460669 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.36 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914250
 protein coding gene Chr13:27443419-27460669 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020394
 protein coding gene Chr13:24878092-24895835 (+)
A/J MGP_AJ_G0020345
 protein coding gene Chr13:24347417-24359100 (+)
AKR/J MGP_AKRJ_G0020325
 protein coding gene Chr13:24687118-24704800 (+)
BALB/cJ MGP_BALBcJ_G0020343
 protein coding gene Chr13:24350424-24361610 (+)
C3H/HeJ MGP_C3HHeJ_G0020146
 protein coding gene Chr13:24749132-24768331 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020780
 protein coding gene Chr13:25750248-25769190 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018365
 protein coding gene Chr13:22979778-22990704 (+)
CAST/EiJ MGP_CASTEiJ_G0019664
 protein coding gene Chr13:24441285-24466111 (+)
CBA/J MGP_CBAJ_G0020100
 protein coding gene Chr13:26815625-26832456 (+)
DBA/2J MGP_DBA2J_G0020224
 protein coding gene Chr13:23877668-23896727 (+)
FVB/NJ MGP_FVBNJ_G0020210
 protein coding gene Chr13:23488500-23505615 (+)
LP/J MGP_LPJ_G0020300
 protein coding gene Chr13:25146143-25161921 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020238
 protein coding gene Chr13:27072821-27087626 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020820
 protein coding gene Chr13:24533664-24545591 (+)
PWK/PhJ MGP_PWKPhJ_G0019418
 protein coding gene Chr13:23790548-23807917 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019234
 protein coding gene Chr13:23440903-23453502 (+)
WSB/EiJ MGP_WSBEiJ_G0019724
 protein coding gene Chr13:24707710-24721547 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prl3a1
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    12
  • cDNA Data
    16
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67000 NCBI Gene Model | MGI Sequence Detail 17198 C57BL/6J ±  kb
transcript NM_025896 RefSeq | MGI Sequence Detail 1308 C57BL/6  
polypeptide NP_080172 RefSeq | MGI Sequence Detail 227 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR018116 Somatotropin hormone, conserved site
    IPR001400 Somatotropin/prolactin
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 9
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:333829 Lopez-Tello J, et al., Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory