About   Help   FAQ
Psmd5 Gene Detail
Summary
  • Symbol
    Psmd5
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • Synonyms
    1500032A03Rik, S5b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914248
    NCBI Gene: 66998
  • Gene Overview
    MyGene.info: PSMD5
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:34852087-34870962 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 22.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914248
protein coding gene Chr2:34849734-34874968 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025643
protein coding gene Chr2:33464681-33489882 (-)
A/J MGP_AJ_G0025620
protein coding gene Chr2:32045070-32070162 (-)
AKR/J MGP_AKRJ_G0025590
protein coding gene Chr2:33175436-33203614 (-)
BALB/cJ MGP_BALBcJ_G0025617
protein coding gene Chr2:32153052-32178394 (-)
C3H/HeJ MGP_C3HHeJ_G0025377
protein coding gene Chr2:33067300-33092668 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026061
protein coding gene Chr2:34433904-34460496 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023470
protein coding gene Chr2:30734121-30759211 (-)
CAST/EiJ MGP_CASTEiJ_G0024839
protein coding gene Chr2:33055825-33082041 (-)
CBA/J MGP_CBAJ_G0025355
protein coding gene Chr2:35767373-35791998 (-)
DBA/2J MGP_DBA2J_G0025488
protein coding gene Chr2:31811205-31836591 (-)
FVB/NJ MGP_FVBNJ_G0025450
protein coding gene Chr2:31704460-31730588 (-)
LP/J MGP_LPJ_G0025574
protein coding gene Chr2:33383507-33409533 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025481
protein coding gene Chr2:35280215-35313612 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026119
protein coding gene Chr2:33061608-33086054 (-)
PWK/PhJ MGP_PWKPhJ_G0024587
protein coding gene Chr2:31724258-31748662 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024387
protein coding gene Chr2:33222168-33251875 (-)
WSB/EiJ MGP_WSBEiJ_G0024908
protein coding gene Chr2:33238558-33265780 (-)



Homology
more
  • Human Ortholog
    PSMD5, proteasome 26S subunit, non-ATPase 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMD5, proteasome 26S subunit, non-ATPase 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    S5B
  • Links
    NCBI Gene ID: 5711
    neXtProt AC: NX_Q16401
    UniProt: Q16401

  • Chr Location
    9q33.2; chr9:120798318-120843021 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37999
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PSMD5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66998 NCBI Gene Model | MGI Sequence Detail 18876 C57BL/6J ±  kb
transcript NM_080554 RefSeq | MGI Sequence Detail 2065 C57BL/6  
polypeptide Q8BJY1 UniProt | EBI | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139349, MGI:2139549
References
more
  • Summaries
    All 36
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:229228 Shim SM, et al., Role of S5b/PSMD5 in proteasome inhibition caused by TNF-alpha/NFkappaB in higher eukaryotes. Cell Rep. 2012 Sep 27;2(3):603-15

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory