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Cep19 Gene Detail
Summary
  • Symbol
    Cep19
  • Name
    centrosomal protein 19
  • Synonyms
    1500031L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914244
    NCBI Gene: 66994
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:31918618-31926875 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 22.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914244
protein coding gene Chr16:31918618-31926887 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022729
protein coding gene Chr16:30133184-30142456 (+)
A/J MGP_AJ_G0022694
protein coding gene Chr16:28729435-28738643 (+)
AKR/J MGP_AKRJ_G0022667
protein coding gene Chr16:29774389-29786008 (+)
BALB/cJ MGP_BALBcJ_G0022696
protein coding gene Chr16:28882148-28890438 (+)
C3H/HeJ MGP_C3HHeJ_G0022461
protein coding gene Chr16:29896960-29910254 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023145
protein coding gene Chr16:30779147-30787278 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020663
protein coding gene Chr16:29103489-29111500 (+)
CAST/EiJ MGP_CASTEiJ_G0021989
protein coding gene Chr16:30027374-30035816 (+)
CBA/J MGP_CBAJ_G0022431
protein coding gene Chr16:32034815-32043000 (+)
DBA/2J MGP_DBA2J_G0022564
protein coding gene Chr16:28583229-28591495 (+)
FVB/NJ MGP_FVBNJ_G0022539
protein coding gene Chr16:28565506-28573830 (+)
LP/J MGP_LPJ_G0022631
protein coding gene Chr16:29913240-29924322 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022558
protein coding gene Chr16:31486851-31494805 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023157
protein coding gene Chr16:29752456-29761002 (+)
PWK/PhJ MGP_PWKPhJ_G0021728
protein coding gene Chr16:28899696-28908046 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021559
protein coding gene Chr16:29550616-29559370 (+)
WSB/EiJ MGP_WSBEiJ_G0022033
protein coding gene Chr16:29690997-29698908 (+)



Homology
more
  • Human Ortholog
    CEP19, centrosomal protein 19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP19, centrosomal protein 19
  • Synonyms
    C3orf34, MOSPGF
  • Links
    NCBI Gene ID: 84984
    neXtProt AC: NX_Q96LK0
    UniProt: Q96LK0

  • Chr Location
    3q29; chr3:196706277-196712250 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 3 alleles in 3 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit obesity, hyperphagia, glucose intolerant and insulin resistant.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66994 NCBI Gene Model | MGI Sequence Detail 8258 C57BL/6J ±  kb
    transcript NM_001416014 RefSeq | MGI Sequence Detail 1738 C57BL/6  
    polypeptide Q9CQA8 UniProt | EBI | MGI Sequence Detail 163 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2146429, MGI:2146522
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:327759 Pollak RM, et al., Metabolic effects of the schizophrenia-associated 3q29 deletion. Transl Psychiatry. 2022 Feb 17;12(1):66

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory