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Med19 Gene Detail
Summary
  • Symbol
    Med19
  • Name
    mediator complex subunit 19
  • Synonyms
    2410018M14Rik, 3110040A13Rik, LCMR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914234
    NCBI Gene: 381379
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:84678402-84688215 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 49.45 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914234
protein coding gene Chr2:84678402-84688215 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025905
protein coding gene Chr2:85360018-85370358 (+)
A/J MGP_AJ_G0025879
protein coding gene Chr2:82063449-82073910 (+)
AKR/J MGP_AKRJ_G0025849
protein coding gene Chr2:84173526-84183458 (+)
BALB/cJ MGP_BALBcJ_G0025876
protein coding gene Chr2:82195156-82205221 (+)
C3H/HeJ MGP_C3HHeJ_G0025635
protein coding gene Chr2:84420940-84430622 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026322
protein coding gene Chr2:88010724-88020278 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023724
protein coding gene Chr2:78889096-78898340 (+)
CAST/EiJ MGP_CASTEiJ_G0025096
protein coding gene Chr2:84942182-84952864 (+)
CBA/J MGP_CBAJ_G0025616
protein coding gene Chr2:91157489-91167260 (+)
DBA/2J MGP_DBA2J_G0025747
protein coding gene Chr2:81601889-81611426 (+)
FVB/NJ MGP_FVBNJ_G0025710
protein coding gene Chr2:80853069-80862656 (+)
LP/J MGP_LPJ_G0025835
protein coding gene Chr2:85163337-85172906 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025740
protein coding gene Chr2:93477262-93486818 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026378
protein coding gene Chr2:84403125-84412687 (+)
PWK/PhJ MGP_PWKPhJ_G0024840
protein coding gene Chr2:81439507-81449534 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024644
protein coding gene Chr2:84554822-84561635 (+)
WSB/EiJ MGP_WSBEiJ_G0025166
protein coding gene Chr2:85082870-85092426 (+)



Homology
more
  • Human Ortholog
    MED19, mediator complex subunit 19
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MED19, mediator complex subunit 19
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DT2P1G7, LCMR1, MED19AS
  • Links
    NCBI Gene ID: 219541
    neXtProt AC: NX_A0JLT2
    UniProt: A0JLT2

  • Chr Location
    11q12.1; chr11:57703709-57712323 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14684
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MED19
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381379 NCBI Gene Model | MGI Sequence Detail 9814 C57BL/6J ±  kb
transcript NM_025885 RefSeq | MGI Sequence Detail 2075 C57BL/6  
polypeptide Q8C1S0 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR019403 Mediator complex, subunit Med19, metazoa
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920427
References
more
  • Summaries
    All 37
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:227263 Fabre PJ, et al., Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13964-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory