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Nuf2 Gene Detail
Summary
  • Symbol
    Nuf2
  • Name
    NUF2, NDC80 kinetochore complex component
  • Synonyms
    2410003C07Rik, Cdca1, Nuf2R
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914227
    NCBI Gene: 66977
  • Gene Overview
    MyGene.info: NUF2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:169497934-169531464 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 76.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    550 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914227
protein coding gene Chr1:169497934-169531464 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016719
protein coding gene Chr1:175130480-175166570 (-)
A/J MGP_AJ_G0016699
protein coding gene Chr1:167980426-168013512 (-)
AKR/J MGP_AKRJ_G0016665
protein coding gene Chr1:173056690-173103393 (-)
BALB/cJ MGP_BALBcJ_G0016660
protein coding gene Chr1:168489671-168527126 (-)
C3H/HeJ MGP_C3HHeJ_G0016484
protein coding gene Chr1:173286776-173322602 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017121
protein coding gene Chr1:180956207-180992908 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014830
protein coding gene Chr1:159770180-159803976 (-)
CAST/EiJ MGP_CASTEiJ_G0016064
protein coding gene Chr1:172914241-172950982 (-)
CBA/J MGP_CBAJ_G0016459
protein coding gene Chr1:187392387-187433241 (-)
DBA/2J MGP_DBA2J_G0016565
protein coding gene Chr1:166869918-166902794 (-)
FVB/NJ MGP_FVBNJ_G0016563
protein coding gene Chr1:165256720-165290961 (-)
LP/J MGP_LPJ_G0016636
protein coding gene Chr1:176193181-176228292 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016588
protein coding gene Chr1:194715487-194751905 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017158
protein coding gene Chr1:172937050-172971462 (-)
PWK/PhJ MGP_PWKPhJ_G0015850
protein coding gene Chr1:166083317-166117031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015636
protein coding gene Chr1:171704062-171739648 (-)
WSB/EiJ MGP_WSBEiJ_G0016126
protein coding gene Chr1:173035596-173087198 (-)



Homology
more
  • Human Ortholog
    NUF2, NDC80 kinetochore complex component NUF2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUF2, NDC80 kinetochore complex component NUF2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDCA1, CT106, NUF2R
  • Links
    NCBI Gene ID: 83540
    neXtProt AC: NX_Q9BZD4
    UniProt: Q9BZD4

  • Chr Location
    1q23.3; chr1:163321933-163355764 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 40205
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NUF2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66977 NCBI Gene Model | MGI Sequence Detail 33531 C57BL/6J ±  kb
transcript NM_001355159 RefSeq | MGI Sequence Detail 2481 C57BL/6  
polypeptide Q99P69 UniProt | EBI | MGI Sequence Detail 463 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 94
    cDNA 92
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138503, MGI:2138707
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory