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Ssbp2 Gene Detail
Summary
  • Symbol
    Ssbp2
  • Name
    single-stranded DNA binding protein 2
  • Synonyms
    1500004K09Rik, 2310079I02Rik, 9330163K02Rik, A830008M03Rik, Hspc116
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914220
    NCBI Gene: 66970
  • Gene Overview
    MyGene.info: SSBP2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:91460283-91703429 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 47.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1950 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914220
protein coding gene Chr13:91460283-91706175 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020807
protein coding gene Chr13:92726430-92997014 (+)
A/J MGP_AJ_G0020761
protein coding gene Chr13:89303384-89558742 (+)
AKR/J MGP_AKRJ_G0020734
protein coding gene Chr13:92013712-92278390 (+)
BALB/cJ MGP_BALBcJ_G0020757
protein coding gene Chr13:89947186-90194835 (+)
C3H/HeJ MGP_C3HHeJ_G0020551
protein coding gene Chr13:91704184-91965480 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021194
protein coding gene Chr13:95591062-95850894 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018762
protein coding gene Chr13:85277345-85518686 (+)
CAST/EiJ MGP_CASTEiJ_G0020070
protein coding gene Chr13:90967878-91230578 (+)
CBA/J MGP_CBAJ_G0020510
protein coding gene Chr13:99365870-99648698 (+)
DBA/2J MGP_DBA2J_G0020635
protein coding gene Chr13:89074429-89320543 (+)
FVB/NJ MGP_FVBNJ_G0020615
protein coding gene Chr13:87892930-88137499 (+)
LP/J MGP_LPJ_G0020708
protein coding gene Chr13:92863573-93117131 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020644
protein coding gene Chr13:99881279-100152080 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021234
protein coding gene Chr13:91426269-91685379 (+)
PWK/PhJ MGP_PWKPhJ_G0019822
protein coding gene Chr13:87816895-88074845 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019646
protein coding gene Chr13:87692643-87949916 (+)
WSB/EiJ MGP_WSBEiJ_G0020127
protein coding gene Chr13:91906530-92164534 (+)



Homology
more
  • Human Ortholog
    SSBP2, single stranded DNA binding protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SSBP2, single stranded DNA binding protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC116, SOSS-B2
  • Links
    NCBI Gene ID: 23635
    neXtProt AC: NX_P81877
    UniProt: P81877

  • Chr Location
    5q14.1; chr5:81417360-81751253 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    30 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice exhibit some perinatal lethality and premature death associated with increased incidence of lymphoma and carcinoma.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000003992 Ensembl Gene Model | MGI Sequence Detail 243147 C57BL/6J ±  kb
    transcript ENSMUST00000004094 Ensembl | MGI Sequence Detail 3957 Not Applicable  
    polypeptide ENSMUSP00000004094 Ensembl | MGI Sequence Detail 361 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR006594 LIS1 homology motif
      IPR008116 Sequence-specific single-strand DNA-binding protein
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 21

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1923746, MGI:2145381, MGI:2145460, MGI:2442615, MGI:2442986
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:240146 Lee B, et al., Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities. Development. 2016 May 15;143(10):1721-31

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory