About   Help   FAQ
Plin5
Gene Detail
 Symbol
Name
ID
Plin5
perilipin 5
MGI:1914218
Synonyms 2310076L09Rik, Lsdp5, MLDP
Feature Type protein coding gene
Genetic Map
Chromosome 17
29.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:56111601-56117596 bp, - strand
From VEGA annotation of GRCm38

  5996 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41654  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: lipid droplet-associated protein, perilipin type
Gene Tree: Plin5

Human
homologs
Human Homolog PLIN5, perilipin 5
NCBI Gene ID 440503
neXtProt AC  NX_Q00G26
Human Synonyms  LSDA5, LSDP5, MLDP, OXPAT
Human Chr (Location)  19p13.3; chr19:4522531-4535196 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knoc-out allele exhibit excessive fatty acid oxidation, abnormal lipid levels in organs depending on fed or fasted state, increased oxygen consumption and activity in the dark phase, and decreased cardiac muscle contractility in aged mice.
 
Phenotype Images(1)
Interactions
Plin5 interacts with 68 markers (Mir34a, Mir34b, Mir34c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process lipid metabolic process, lipid particle organization, ...
Component cytoplasm, cytosol, ...
Function identical protein binding, lipase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000035787 (Evidence)
Ensembl Gene ModelENSMUSG00000011305 (Evidence)
Entrez Gene66968 (Evidence)
UniGene254985
DFCITC1586170, TC1676077
DoTSDT.40156071, DT.529197
NIA Mouse Gene IndexU037938
Consensus CDS ProjectCCDS37662.1
International Mouse Knockout Project StatusPlin5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035787 VEGA Gene Model | MGI Sequence Detail 5996 C57BL/6J ±  kb
transcript OTTMUST00000091587 VEGA | MGI Sequence Detail 1986 Not Applicable 
polypeptide OTTMUSP00000050461 VEGA | MGI Sequence Detail 463 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004279 Perilipin
Protein Ontology PR:000009952 perilipin-5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199487 Bindesboll C, et al., Fatty acids regulate perilipin5 in muscle by activating PPARdelta. J Lipid Res. 2013 Jul;54(7):1949-63
All references(42)
Other
accession IDs
MGI:2146846, MGI:2147046

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory