Plin5
Gene Detail

Symbol Name ID

Plin5 perilipin 5 MGI:1914218

Synonyms

2310076L09Rik, Lsdp5, MLDP

Feature Type

protein coding gene

Genetic Map

Chromosome 17

29.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:56111601-56117596 bp, - strand From VEGA annotation of GRCm38   5996 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41654  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: lipid droplet-associated protein, perilipin type
Gene Tree: Plin5

Human homologs

Human Homolog		PLIN5, perilipin 5
NCBI Gene ID		440503
neXtProt AC		NX_Q00G26
Human Synonyms		LSDA5, LSDP5, MLDP, OXPAT
Human Chr (Location)		19p13.3; chr19:4522543-4535208 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knoc-out allele exhibit excessive fatty acid oxidation, abnormal lipid levels in organs depending on fed or fasted state, increased oxygen consumption and activity in the dark phase, and decreased cardiac muscle contractility in aged mice.

 

Gene Ontology (GO) classifications

All GO classifications: (1 annotations)

Component

lipid particle

External Resources: FuncBase

Expression

Literature Summary: (2 records)
cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(13)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000035787 (Evidence)
Ensembl Gene Model	ENSMUSG00000011305 (Evidence)
Entrez Gene	66968 (Evidence)
UniGene	254985
DFCI	TC1586170, TC1676077
DoTS	DT.40156071, DT.529197
NIA Mouse Gene Index	U037938
Consensus CDS Project	CCDS37662.1
International Mouse Knockout Project Status	Plin5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035787	VEGA Gene Model | MGI Sequence Detail	5996	C57BL/6J
transcript	OTTMUST00000091587	VEGA | MGI Sequence Detail	1986	Not Applicable
polypeptide	OTTMUSP00000050461	VEGA | MGI Sequence Detail	463	Not Applicable

All sequences(30) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(25 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004279	Perilipin
Protein Ontology	PR:000009952	lipid storage droplet protein 5

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:188390 Kuramoto K, et al., Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem. 2012 Jul 6;287(28):23852-63
All references(33)

Other accession IDs

MGI:2146846, MGI:2147046