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Plin5
Gene Detail
Symbol

Name
ID
Plin5
perilipin 5
MGI:1914218
Synonyms
2310076L09Rik, Lsdp5, MLDP
Feature Type
protein coding gene
Genetic Map
Chromosome 17
29.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:56111601-56117596 bp, - strand
From VEGA annotation of GRCm38

  5996 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41654  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: PLIN5
Protein SuperFamily: lipid droplet-associated protein, perilipin type
Gene Tree: Plin5

Human
homologs
PLIN5, perilipin 5
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 440503
neXtProt AC: NX_Q00G26

Human Synonyms: LSDA5, LSDP5, MLDP, OXPAT

Human Chr (Location): 19p13.3; chr19:4522531-4535196 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knoc-out allele exhibit excessive fatty acid oxidation, abnormal lipid levels in organs depending on fed or fasted state, increased oxygen consumption and activity in the dark phase, and decreased cardiac muscle contractility in aged mice.
 
Phenotype Images(1)
Interactions
Plin5 interacts with 68 markers (Mir34a, Mir34b, Mir34c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process lipid metabolic process, lipid particle organization, ...
Component cytoplasm, cytosol, ...
Function identical protein binding, lipase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000035787 (Evidence)
Ensembl Gene Model ENSMUSG00000011305 (Evidence)
Entrez Gene 66968 (Evidence)
UniGene 254985
DFCI TC1676077, TC1586170
DoTS DT.40156071, DT.529197
NIA Mouse Gene Index U037938
Consensus CDS Project CCDS37662.1
International Mouse Phenotyping Consortium Status Plin5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035787 VEGA Gene Model | MGI Sequence Detail 5996 C57BL/6J ±  kb
transcript OTTMUST00000091587 VEGA | MGI Sequence Detail 1986 Not Applicable 
polypeptide OTTMUSP00000050461 VEGA | MGI Sequence Detail 463 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004279 Perilipin
Protein Ontology PR:000009952 perilipin-5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:218384 Pollak NM, et al., The interplay of protein kinase a and perilipin 5 regulates cardiac lipolysis. J Biol Chem. 2015 Jan 16;290(3):1295-306
All references(42)
Other
accession IDs
MGI:2146846, MGI:2147046

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory