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Edem3 Gene Detail
Summary
  • Symbol
    Edem3
  • Name
    ER degradation enhancer, mannosidase alpha-like 3
  • Synonyms
    2310050N11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914217
    NCBI Gene: 66967
  • Gene Overview
    MyGene.info: EDEM3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:151755371-151822051 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 64.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    580 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914217
protein coding gene Chr1:151755344-151822328 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016584
protein coding gene Chr1:156503539-156569660 (+)
A/J MGP_AJ_G0016566
protein coding gene Chr1:150186456-150252557 (+)
AKR/J MGP_AKRJ_G0016531
protein coding gene Chr1:154819931-154890962 (+)
BALB/cJ MGP_BALBcJ_G0016526
protein coding gene Chr1:150756878-150822287 (+)
C3H/HeJ MGP_C3HHeJ_G0016351
protein coding gene Chr1:154939955-155005793 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016987
protein coding gene Chr1:161919689-161986168 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014696
protein coding gene Chr1:142515183-142581358 (+)
CAST/EiJ MGP_CASTEiJ_G0015930
protein coding gene Chr1:154385325-154455944 (+)
CBA/J MGP_CBAJ_G0016325
protein coding gene Chr1:167615797-167687268 (+)
DBA/2J MGP_DBA2J_G0016431
protein coding gene Chr1:149226347-149291597 (+)
FVB/NJ MGP_FVBNJ_G0016429
protein coding gene Chr1:147682360-147747191 (+)
LP/J MGP_LPJ_G0016502
protein coding gene Chr1:157578262-157644744 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016455
protein coding gene Chr1:175298822-175365162 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017023
protein coding gene Chr1:154579687-154649632 (+)
PWK/PhJ MGP_PWKPhJ_G0015716
protein coding gene Chr1:148196820-148262589 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015503
protein coding gene Chr1:153418860-153485445 (+)
WSB/EiJ MGP_WSBEiJ_G0015993
protein coding gene Chr1:154671108-154738566 (+)



Homology
more
  • Human Ortholog
    EDEM3, ER degradation enhancing alpha-mannosidase like protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EDEM3, ER degradation enhancing alpha-mannosidase like protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf22
  • Links
    NCBI Gene ID: 80267
    neXtProt AC: NX_Q9BZQ6
    UniProt: Q9BZQ6

  • Chr Location
    1q25.3; chr1:184690491-184754907 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11866
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EDEM3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043019 Ensembl Gene Model | MGI Sequence Detail 66681 C57BL/6J ±  kb
transcript ENSMUST00000188145 Ensembl | MGI Sequence Detail 3262 Not Applicable  
polypeptide ENSMUSP00000140443 Ensembl | MGI Sequence Detail 947 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory