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Neat1 Gene Detail
Summary
  • Symbol
    Neat1
  • Name
    nuclear paraspeckle assembly transcript 1 (non-protein coding)
  • Synonyms
    2310043N10Rik
  • Feature Type
    lincRNA gene
  • IDs
    MGI:1914211
    NCBI Gene: 66961
  • Gene Overview
    MyGene.info: NEAT1
Location & Maps
more
  • Sequence Map
    Chr19:5824708-5845478 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20771 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NEAT1, nuclear paraspeckle assembly transcript 1 (non-protein coding)
  • Human Ortholog
    NEAT1, nuclear paraspeckle assembly transcript 1 (non-protein coding)
    Orthology source: HGNC
  • Synonyms
    LINC00084, NCRNA00084, TncRNA, VINC
  • Links
    NCBI Gene ID: 283131

  • Chr Location
    11q13.1; chr11:65422798-65426532 (+)  GRCh38.p2

  • HCOP
    human homology predictions: NEAT1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    52
  • Gene trapped
    51
  • Targeted
    1
Mice homozygous for a null mutation lack paraspeckles in the nucleus and exhibit reduced pup survival associated with impaired mammary gland development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037797 VEGA Gene Model | MGI Sequence Detail 20771 C57BL/6J ±  kb
transcript OTTMUST00000097543 VEGA | MGI Sequence Detail 20771 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    147 from dbSNP Build 142
Molecular
Reagents
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  • All nucleic 20
    cDNA 13
    Primer pair 6
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233000 Gornikiewicz B, et al., Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential. BMC Genomics. 2016;17:231

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory