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Tmx2 Gene Detail
Summary
  • Symbol
    Tmx2
  • Name
    thioredoxin-related transmembrane protein 2
  • Synonyms
    2310042M24Rik, Txndc14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914208
    NCBI Gene: 66958
Location & Maps
more
  • Sequence Map
    Chr2:84671316-84679140 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7825 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 49.45 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMX2, thioredoxin related transmembrane protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMX2, thioredoxin related transmembrane protein 2
    Orthology source: HomoloGene
  • Synonyms
    CGI-31, PDIA12, PIG26, TXNDC14
  • Links
    NCBI Gene ID: 51075
    neXtProt AC: NX_Q9Y320

  • Chr Location
    11cen-q22.3; chr11:57712523-57740973 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9317
    1 human;1 mouse;1 rat;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TMX2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    3 involving Tmx2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013511 VEGA Gene Model | MGI Sequence Detail 7825 C57BL/6J ±  kb
transcript OTTMUST00000032636 VEGA | MGI Sequence Detail 2282 Not Applicable  
polypeptide OTTMUSP00000014508 VEGA | MGI Sequence Detail 295 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    46 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029819 thioredoxin-related transmembrane protein 2
  • InterPro Domains
    IPR013766 Thioredoxin domain
    IPR012336 Thioredoxin-like fold
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146774
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory