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Serpinb11 Gene Detail
Summary
  • Symbol
    Serpinb11
  • Name
    serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
  • Synonyms
    2310046M08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914207
    NCBI Gene: 66957
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:107290044-107308205 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 50.34 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914207
protein coding gene Chr1:107288928-107308205 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016380
protein coding gene Chr1:109604433-109623707 (+)
A/J MGP_AJ_G0016361
protein coding gene Chr1:105785193-105804498 (+)
AKR/J MGP_AKRJ_G0016324
protein coding gene Chr1:108701298-108720599 (+)
BALB/cJ MGP_BALBcJ_G0016320
protein coding gene Chr1:105890294-105909567 (+)
C3H/HeJ MGP_C3HHeJ_G0016147
protein coding gene Chr1:109118144-109137447 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016779
protein coding gene Chr1:113762335-113781612 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014497
protein coding gene Chr1:99908993-99928380 (+)
CAST/EiJ MGP_CASTEiJ_G0015730
protein coding gene Chr1:108046259-108065541 (+)
CBA/J MGP_CBAJ_G0016119
protein coding gene Chr1:117646736-117666039 (+)
DBA/2J MGP_DBA2J_G0016226
protein coding gene Chr1:104811784-104831058 (+)
FVB/NJ MGP_FVBNJ_G0016225
protein coding gene Chr1:103765002-103784849 (+)
LP/J MGP_LPJ_G0016299
protein coding gene Chr1:110880982-110900258 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016252
protein coding gene Chr1:122078138-122097413 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016817
protein coding gene Chr1:108686568-108705876 (+)
PWK/PhJ MGP_PWKPhJ_G0015515
protein coding gene Chr1:103852979-103872331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015303
protein coding gene Chr1:107345942-107365318 (+)
WSB/EiJ MGP_WSBEiJ_G0015792
protein coding gene Chr1:108586091-108605339 (+)



Homology
more
  • Human Ortholog
    SERPINB11, serpin family B member 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINB11, serpin family B member 11
  • Synonyms
    EPIPIN, SERPIN11
  • Links
    NCBI Gene ID: 89778
    neXtProt AC: NX_Q96P15
    UniProt: Q96P15

  • Chr Location
    18q21.33; chr18:63647579-63726432 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66957 NCBI Gene Model | MGI Sequence Detail 18162 C57BL/6J ±  kb
transcript NM_025867 RefSeq | MGI Sequence Detail 1699 C57BL/6  
polypeptide Q9CQV3 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    Genomic 3
    cDNA 25
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138410
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:306806 Hauser BR, et al., Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development. iScience. 2020 Dec 18;23(12):101838

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory