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Cdca7 Gene Detail
Summary
  • Symbol
    Cdca7
  • Name
    cell division cycle associated 7
  • Synonyms
    2310021G01Rik, JPO1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914203
    NCBI Gene: 66953
  • Gene Overview
    MyGene.info: CDCA7
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:72476198-72486890 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 43.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    128 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914203
protein coding gene Chr2:72476159-72486893 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025830
protein coding gene Chr2:72665841-72676224 (+)
A/J MGP_AJ_G0025808
protein coding gene Chr2:69811763-69822450 (+)
AKR/J MGP_AKRJ_G0025776
protein coding gene Chr2:71751936-71762713 (+)
BALB/cJ MGP_BALBcJ_G0025802
protein coding gene Chr2:70025882-70036392 (+)
C3H/HeJ MGP_C3HHeJ_G0025562
protein coding gene Chr2:71938097-71950489 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026249
protein coding gene Chr2:74845244-74860640 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023652
protein coding gene Chr2:67051255-67061632 (+)
CAST/EiJ MGP_CASTEiJ_G0025026
protein coding gene Chr2:72147146-72157880 (+)
CBA/J MGP_CBAJ_G0025543
protein coding gene Chr2:77588086-77598805 (+)
DBA/2J MGP_DBA2J_G0025674
protein coding gene Chr2:69440904-69452201 (+)
FVB/NJ MGP_FVBNJ_G0025636
protein coding gene Chr2:68851363-68862759 (+)
LP/J MGP_LPJ_G0025762
protein coding gene Chr2:72549894-72560273 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025667
protein coding gene Chr2:79536410-79548860 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026306
protein coding gene Chr2:71822981-71833699 (+)
PWK/PhJ MGP_PWKPhJ_G0024767
protein coding gene Chr2:69327599-69338138 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024575
protein coding gene Chr2:72031645-72044472 (+)
WSB/EiJ MGP_WSBEiJ_G0025094
protein coding gene Chr2:72279806-72290157 (+)



Homology
more
  • Human Ortholog
    CDCA7, cell division cycle associated 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDCA7, cell division cycle associated 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ICF3, JPO1
  • Links
    NCBI Gene ID: 83879
    neXtProt AC: NX_Q9BWT1
    UniProt: Q9BWT1

  • Chr Location
    2q31.1; chr2:173354017-173368992 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 49970
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CDCA7
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human CDCA7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66953 NCBI Gene Model | MGI Sequence Detail 10693 C57BL/6J ±  kb
transcript NM_025866 RefSeq | MGI Sequence Detail 2361 C57BL/6  
polypeptide Q9D0M2 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005224 cell division cycle-associated protein 7
  • InterPro Domains
    IPR033576 Cell division cycle-associated protein 7
    IPR018866 Zinc-finger domain of monoamine-oxidase A repressor R1
Molecular
Reagents
less
  • All nucleic 151
    cDNA 148
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146580
References
more
  • Summaries
    All 57
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:149 Morelli L, et al., Heterogeneity of natural killer cell subsets in NK-1.1+ and NK-1.1- inbred mouse strains and their progeny. Cell Immunol. 1992 Apr 15;141(1):148-60
  • Latest
    J:264125 Xu Z, et al., SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory