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Cdca7 Gene Detail
Summary
  • Symbol
    Cdca7
  • Name
    cell division cycle associated 7
  • Synonyms
    2310021G01Rik, JPO1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914203
    NCBI Gene: 66953
  • Gene Overview
    MyGene.info: CDCA7
Location & Maps
more
  • Sequence Map
    Chr2:72476159-72486893 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10735 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 43.35 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CDCA7, cell division cycle associated 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDCA7, cell division cycle associated 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ICF3, JPO1
  • Links
    NCBI Gene ID: 83879
    neXtProt AC: NX_Q9BWT1

  • Chr Location
    2q31; chr2:173354017-173368990 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49970
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CDCA7
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human CDCA7 associations

Human Disease Mouse Models
       Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 3; ICF3   OMIM: 616910
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    21
  • Chemically induced (other)
    1
  • Gene trapped
    12
  • Targeted
    8
  • Genomic Mutations
    7 involving Cdca7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013166 VEGA Gene Model | MGI Sequence Detail 10735 C57BL/6J ±  kb
transcript OTTMUST00000031801 VEGA | MGI Sequence Detail 2424 Not Applicable  
polypeptide OTTMUSP00000014171 VEGA | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    128 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005224 cell division cycle-associated protein 7
  • InterPro Domains
    IPR033576 Cell division cycle-associated protein 7
    IPR018866 Zinc-finger domain of monoamine-oxidase A repressor R1
Molecular
Reagents
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  • All nucleic 149
    cDNA 147
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGI:2146580
References
more
  • Summaries
    All 41
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 17
  • Earliest
    J:149 Morelli L, et al., Heterogeneity of natural killer cell subsets in NK-1.1+ and NK-1.1- inbred mouse strains and their progeny. Cell Immunol. 1992 Apr 15;141(1):148-60
  • Latest
    J:217538 Lui JH, et al., Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. Nature. 2014 Nov 13;515(7526):264-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory