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Acad8
Gene Detail
 Symbol
Name
ID
Acad8
acyl-Coenzyme A dehydrogenase family, member 8
MGI:1914198
Synonyms 2310016C19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 9
12.00 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:26974135-26999566 bp, - strand
From VEGA annotation of GRCm38

  25432 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Acad8

Human
homologs
Human Homolog ACAD8, acyl-CoA dehydrogenase family, member 8
NCBI Gene ID 27034
neXtProt AC  NX_Q9UKU7
Human Synonyms  ACAD-8, ARC42
Human Chr (Location)  11q25; chr11:134253537-134265855 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ACAD8
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from APF )
Interactions
Acad8 interacts with 190 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process branched-chain amino acid catabolic process, metabolic process, ...
Component mitochondrion
Function 2-methylhexanoyl-CoA dehydrogenase activity, 4-methyloctanoyl-CoA dehydrogenase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (116)    Tissues (96)    Images (28)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 116
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000029982 (Evidence)
Ensembl Gene ModelENSMUSG00000031969 (Evidence)
Entrez Gene66948 (Evidence)
DFCITC1576545, TC1636817
DoTSDT.101312415, DT.101386889, DT.491414, DT.97378441, DT.99842783
NIA Mouse Gene IndexU030631
EC1.3.99.-
Consensus CDS ProjectCCDS40567.1
International Mouse Knockout Project StatusAcad8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029982 VEGA Gene Model | MGI Sequence Detail 25432 C57BL/6J ±  kb
transcript OTTMUST00000074352 VEGA | MGI Sequence Detail 2885 Not Applicable 
polypeptide OTTMUSP00000038677 VEGA | MGI Sequence Detail 413 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(133 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006089 Acyl-CoA dehydrogenase, conserved site
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Protein Ontology PR:000003598 isobutyryl-CoA dehydrogenase, mitochondrial
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)
Other
accession IDs
MGI:2143118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory