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Slc66a2 Gene Detail
Summary
  • Symbol
    Slc66a2
  • Name
    solute carrier family 66 member 2
  • Synonyms
    2310009N05Rik, 4933425L21Rik, 5730564E11Rik, C78974, Pqlc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914193
    NCBI Gene: 66943
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80298458-80335940 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 53.37 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1383 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914193
 protein coding gene Chr18:80296507-80335940 (+)
129S1/SvImJ ENSMUSG00200028643
 protein coding gene Chr18:77514017-77552963 (+)
A/J ENSMUSG00195004835
 protein coding gene Chr18:77597804-77637230 (+)
AKR/J ENSMUSG00220017035
 protein coding gene Chr18:77543019-77581652 (+)
BALB/cJ ENSMUSG00180013323
 protein coding gene Chr18:78168027-78207469 (+)
C3H/HeJ ENSMUSG00175012116
 protein coding gene Chr18:77713627-77753046 (+)
C57BL/6NJ ENSMUSG00215016960
 protein coding gene Chr18:77075839-77115273 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022437
 protein coding gene Chr18:76465361-76505716 (+)
CAST/EiJ ENSTCUG00005026795
 protein coding gene Chr18:76633024-76671882 (+)
CBA/J ENSMUSG00210031298
 protein coding gene Chr18:77664213-77703632 (+)
DBA/2J ENSMUSG00185011162
 protein coding gene Chr18:77569450-77608867 (+)
FVB/NJ ENSMUSG00205012709
 protein coding gene Chr18:76990871-77030345 (+)
JF1/MsJ ENSUMUG00000024275
 protein coding gene Chr18:77481880-77520510 (+)
LP/J ENSMUSG00230011372
 protein coding gene Chr18:79620314-79659260 (+)
NOD/ShiLtJ ENSMUSG00190020230
 protein coding gene Chr18:77370132-77409570 (+)
NZO/HlLtJ ENSMUSG00225033322
 protein coding gene Chr18:79502809-79539710 (+)
PWK/PhJ ENSLUMG00010006862
 protein coding gene Chr18:77869909-77909028 (+)
SPRET/EiJ ENSMSPG00010008197
 protein coding gene Chr18:78232565-78270855 (+)
WSB/EiJ ENSIUOG00005007704
 protein coding gene Chr18:77046666-77085865 (+)



Homology
more
  • Human Ortholog
    SLC66A2, solute carrier family 66 member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC66A2, solute carrier family 66 member 2
  • Synonyms
    PQLC1
  • Links
    NCBI Gene ID: 80148
    UniProt: Q8N2U9

  • Chr Location
    18q23; chr18:79902420-79951676 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    673
  • Tissues
    10
  • cDNA Data
    103
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66943 NCBI Gene Model | MGI Sequence Detail 37483 C57BL/6J ±  kb
transcript NM_001164423 RefSeq | MGI Sequence Detail 3254 C57BL/6  
polypeptide Q80XM9 UniProt | EBI | MGI Sequence Detail 271 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    cDNA 103

    Microarray probesets 6
Other
Accession IDs
less
MGI:1917916, MGI:1925388, MGI:2147406, MGI:6369422
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory