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Ddx18 Gene Detail
Summary
  • Symbol
    Ddx18
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
  • Synonyms
    2310005B10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914192
    NCBI Gene: 66942
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:121553835-121567980 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 52.98 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    171 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914192
protein coding gene Chr1:121553835-121567989 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016412
protein coding gene Chr1:124394760-124408598 (-)
A/J MGP_AJ_G0016395
protein coding gene Chr1:119922994-119937118 (-)
AKR/J MGP_AKRJ_G0016360
protein coding gene Chr1:123438910-123460288 (-)
BALB/cJ MGP_BALBcJ_G0016355
protein coding gene Chr1:120204312-120218547 (-)
C3H/HeJ MGP_C3HHeJ_G0016181
protein coding gene Chr1:123615968-123632613 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016816
protein coding gene Chr1:129139040-129156846 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014529
protein coding gene Chr1:113546828-113560420 (-)
CAST/EiJ MGP_CASTEiJ_G0015762
protein coding gene Chr1:122440904-122455085 (-)
CBA/J MGP_CBAJ_G0016154
protein coding gene Chr1:133595313-133610266 (-)
DBA/2J MGP_DBA2J_G0016260
protein coding gene Chr1:118945655-118959799 (-)
FVB/NJ MGP_FVBNJ_G0016259
protein coding gene Chr1:117709354-117725459 (-)
LP/J MGP_LPJ_G0016331
protein coding gene Chr1:125743236-125761404 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016284
protein coding gene Chr1:139273638-139290953 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016852
protein coding gene Chr1:123200475-123214619 (-)
PWK/PhJ MGP_PWKPhJ_G0015548
protein coding gene Chr1:117956496-117971763 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015336
protein coding gene Chr1:122108483-122121771 (-)
WSB/EiJ MGP_WSBEiJ_G0015824
protein coding gene Chr1:123078624-123097497 (-)



Homology
more
  • Human Ortholog
    DDX18, DEAD-box helicase 18
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DDX18, DEAD-box helicase 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Has1, MrDb
  • Links
    NCBI Gene ID: 8886
    neXtProt AC: NX_Q9NVP1
    UniProt: Q9NVP1

  • Chr Location
    2q14.1; chr2:117814679-117832377 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66942 NCBI Gene Model | MGI Sequence Detail 14146 C57BL/6J ±  kb
transcript NM_025860 RefSeq | MGI Sequence Detail 2249 C57BL/6  
polypeptide Q8K363 UniProt | EBI | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 97
    cDNA 97

    Microarray probesets 6
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory