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Aagab Gene Detail
Summary
  • Symbol
    Aagab
  • Name
    alpha- and gamma-adaptin binding protein
  • Synonyms
    2310007F21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914189
    NCBI Gene: 66939
  • Gene Overview
    MyGene.info: AAGAB
Location & Maps
more
  • Sequence Map
    Chr9:63602655-63641889 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39235 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 34.19 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AAGAB, alpha- and gamma-adaptin binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AAGAB, alpha- and gamma-adaptin binding protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KPPP1, p34, PPKP1, PPKP1A
  • Links
    NCBI Gene ID: 79719
    neXtProt AC: NX_Q6PD74

  • Chr Location
    15q23; chr15:67200675-67255198 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11648
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: AAGAB
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human AAGAB associations

Human Disease Mouse Models
       Palmoplantar Keratoderma, Punctate Type IA; PPKP1A   OMIM: 148600
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    9
  • Targeted
    2
  • Genomic Mutations
    1 involving Aagab
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037257 Ensembl Gene Model | MGI Sequence Detail 39235 C57BL/6J ±  kb
transcript ENSMUST00000041551 Ensembl | MGI Sequence Detail 2600 Not Applicable  
polypeptide ENSMUSP00000048595 Ensembl | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    216 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029252 alpha- and gamma-adaptin-binding protein p34
  • InterPro Domains
    IPR019341 Alpha/gamma-adaptin-binding protein p34
Molecular
Reagents
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  • All nucleic 76
    cDNA 76

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory