About   Help   FAQ
Dsn1 Gene Detail
Summary
  • Symbol
    Dsn1
  • Name
    DSN1 homolog, MIS12 kinetochore complex component
  • Synonyms
    1700022L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914184
    NCBI Gene: 66934
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:156837185-156849074 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    295 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914184
 protein coding gene Chr2:156836982-156849074 (-)
129S1/SvImJ ENSMUSG00200015295
 protein coding gene Chr2:153700844-153712731 (-)
A/J ENSMUSG00195018422
 protein coding gene Chr2:154067464-154079348 (-)
AKR/J ENSMUSG00220012390
 protein coding gene Chr2:153369595-153381652 (-)
BALB/cJ ENSMUSG00180048713
 protein coding gene Chr2:153521915-153533806 (-)
C3H/HeJ ENSMUSG00175045829
 protein coding gene Chr2:154272227-154284117 (-)
C57BL/6NJ ENSMUSG00215025227
 protein coding gene Chr2:153686429-153698319 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024567
 protein coding gene Chr2:148944676-148957654 (-)
CAST/EiJ ENSTCUG00005043242
 protein coding gene Chr2:152668320-152680387 (-)
CBA/J ENSMUSG00210016090
 protein coding gene Chr2:154203358-154215246 (-)
DBA/2J ENSMUSG00185047987
 protein coding gene Chr2:153911583-153923639 (-)
FVB/NJ ENSMUSG00205024078
 protein coding gene Chr2:152954308-152966199 (-)
JF1/MsJ ENSUMUG00000018789
 protein coding gene Chr2:153567853-153579910 (-)
LP/J ENSMUSG00230042502
 protein coding gene Chr2:155498570-155510458 (-)
NOD/ShiLtJ ENSMUSG00190036772
 protein coding gene Chr2:153591786-153603675 (-)
NZO/HlLtJ ENSMUSG00225051881
 protein coding gene Chr2:163518689-163530575 (-)
PWK/PhJ ENSLUMG00010042182
 protein coding gene Chr2:153502896-153514968 (-)
SPRET/EiJ ENSMSPG00010028603
 protein coding gene Chr2:156285520-156297574 (-)
WSB/EiJ ENSIUOG00005043565
 protein coding gene Chr2:153282155-153294041 (-)



Homology
more
  • Human Ortholog
    DSN1, DSN1 component of MIS12 kinetochore complex
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DSN1, DSN1 component of MIS12 kinetochore complex
  • Synonyms
    C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13
  • Links
    NCBI Gene ID: 79980
    UniProt: Q9H410

  • Chr Location
    20q11.23; chr20:36751791-36774298 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    9
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    633
  • Tissues
    10
  • cDNA Data
    62
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027635 Ensembl Gene Model | MGI Sequence Detail 11890 C57BL/6J ±  kb
transcript ENSMUST00000103129 Ensembl | MGI Sequence Detail 2080 Not Applicable  
polypeptide ENSMUSP00000099418 Ensembl | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139390
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory