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Rexo1 Gene Detail
Summary
  • Symbol
    Rexo1
  • Name
    REX1, RNA exonuclease 1
  • Synonyms
    1700021P10Rik, 2610511M11Rik, Rex1, Tceb3bp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914182
    NCBI Gene: 66932
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80540922-80561560 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914182
protein coding gene Chr10:80540922-80562271 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017506
protein coding gene Chr10:81164460-81189502 (-)
A/J MGP_AJ_G0017484
protein coding gene Chr10:78326795-78347434 (-)
AKR/J MGP_AKRJ_G0017445
protein coding gene Chr10:80470500-80492516 (-)
BALB/cJ MGP_BALBcJ_G0017446
protein coding gene Chr10:78543704-78564306 (-)
C3H/HeJ MGP_C3HHeJ_G0017269
protein coding gene Chr10:80554064-80575173 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017900
protein coding gene Chr10:83972598-83992879 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015588
protein coding gene Chr10:74536806-74556869 (-)
CAST/EiJ MGP_CASTEiJ_G0016836
protein coding gene Chr10:80777332-80800199 (-)
CBA/J MGP_CBAJ_G0017241
protein coding gene Chr10:87224523-87249505 (-)
DBA/2J MGP_DBA2J_G0017347
protein coding gene Chr10:77528216-77549110 (-)
FVB/NJ MGP_FVBNJ_G0017341
protein coding gene Chr10:76737097-76759391 (-)
LP/J MGP_LPJ_G0017418
protein coding gene Chr10:81636588-81645137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017367
protein coding gene Chr10:89160949-89182749 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017941
protein coding gene Chr10:80453711-80478062 (-)
PWK/PhJ MGP_PWKPhJ_G0016617
protein coding gene Chr10:77410117-77431533 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016406
protein coding gene Chr10:79417751-79437753 (-)
WSB/EiJ MGP_WSBEiJ_G0016896
protein coding gene Chr10:80492739-80515159 (-)



Homology
more
  • Human Ortholog
    REXO1, RNA exonuclease 1 homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    REXO1, RNA exonuclease 1 homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EloA-BP1, ELOABP1, REX1, TCEB3BP1
  • Links
    NCBI Gene ID: 57455
    neXtProt AC: NX_Q8N1G1
    UniProt: Q8N1G1

  • Chr Location
    19p13.3; chr19:1815246-1848684 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41391
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: REXO1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047417 Ensembl Gene Model | MGI Sequence Detail 20639 C57BL/6J ±  kb
transcript ENSMUST00000057910 Ensembl | MGI Sequence Detail 5250 Not Applicable  
polypeptide ENSMUSP00000049705 Ensembl | MGI Sequence Detail 1213 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 124
    cDNA 124

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919749, MGI:2143801
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory