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Chordc1 Gene Detail
Summary
  • Symbol
    Chordc1
  • Name
    cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
  • Synonyms
    1110001O09Rik, Chp-1, morgana
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914167
    NCBI Gene: 66917
Location & Maps
more
  • Sequence Map
    Chr9:18292267-18314000 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21734 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.01 cM, cytoband A3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CHORDC1, cysteine and histidine rich domain containing 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CHORDC1, cysteine and histidine rich domain containing 1
    Orthology source: HomoloGene
  • Synonyms
    CHP1
  • Links
    NCBI Gene ID: 26973
    neXtProt AC: NX_Q9UHD1

  • Chr Location
    11q14.3; chr11:90193947-90223364 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with Chordc1 mouse models

Human Disease Mouse Models
       Leukemia, Chronic Myeloid; CML   OMIM: 608232 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    23 phenotypes from 1 allele in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Gene trapped
    4
  • Targeted
    1
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit embryonic lethality before somite formation with decreased proliferation and increased apoptosis of cultured inner cell masse cells.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001774 Ensembl Gene Model | MGI Sequence Detail 21734 C57BL/6J ±  kb
transcript ENSMUST00000001825 Ensembl | MGI Sequence Detail 2205 Not Applicable  
polypeptide ENSMUSP00000001825 Ensembl | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142930
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:222040 Di Savino A, et al., Morgana acts as an oncosuppressor in chronic myeloid leukemia. Blood. 2015 Apr 2;125(14):2245-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory