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Chordc1
Gene Detail
 Symbol
Name
ID
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
MGI:1914167
Synonyms 1110001O09Rik, Chp-1, morgana
Feature Type protein coding gene
Genetic Map
Chromosome 9
7.01 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:18292267-18314000 bp, + strand
From NCBI annotation of GRCm38

  21734 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Chordc1

Human
homologs
Human Homolog CHORDC1, cysteine and histidine-rich domain (CHORD) containing 1
NCBI Gene ID 26973
neXtProt AC  NX_Q9UHD1
Human Synonyms  CHP1
Human Chr (Location)  11q14.3; chr11:90200429-90223364 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
 
Mice homozygous for a knock-out allele exhibit embryonic lethality before somite formation with decreased proliferation and increased apoptosis of cultured inner cell masse cells.
 
Interactions
Chordc1 interacts with 182 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process chaperone-mediated protein folding, negative regulation of Rho-dependent protein serine/threonine kinase activity, ...
Function Hsp90 protein binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (42)    Tissues (4)    Images (22)
Theiler Stages: 23
Assay TypeResults
RNA in situ 42
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000001774 (Evidence)
Entrez Gene66917 (Evidence)
DFCITC1574669, TC1631921, TC1648114
DoTSDT.40176626, DT.492688, DT.94378477
NIA Mouse Gene IndexU042952
Consensus CDS ProjectCCDS22842.1
International Mouse Knockout Project StatusChordc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 66917 NCBI Gene Model | MGI Sequence Detail 21734 C57BL/6J ±  kb
transcript NM_025844 RefSeq | MGI Sequence Detail 2205 C57BL/6 
polypeptide Q9D1P4 UniProt | EBI | MGI Sequence Detail 331 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(106 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007052 CS-like domain
InterPro IPR007051 Cysteine/histidine-rich domain
InterPro IPR008978 HSP20-like chaperone
Protein Ontology PR:000005445 cysteine and histidine-rich domain-containing protein 1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197112 Hong TJ, et al., Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1. J Biol Chem. 2013 Jan 4;288(1):215-22
All references(37)
Other
accession IDs
MGI:2142930

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory