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Chordc1
Gene Detail
Symbol

Name
ID
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
MGI:1914167
Synonyms
1110001O09Rik, Chp-1, morgana
Feature Type
protein coding gene
Genetic Map
Chromosome 9
7.01 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:18292267-18314000 bp, + strand
From Ensembl annotation of GRCm38

  21734 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CHORDC1
Gene Tree: Chordc1

Human
homologs
CHORDC1, cysteine and histidine-rich domain (CHORD) containing 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 26973
neXtProt AC: NX_Q9UHD1

Human Synonyms: CHP1

Human Chr (Location): 11q14.3; chr11:90193947-90223364 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from CvDC )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality before somite formation with decreased proliferation and increased apoptosis of cultured inner cell masse cells.
 
Interactions
Chordc1 interacts with 181 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (42)    Tissues (4)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase chordc1 ; ZFIN chordc1a, chordc1b    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000001774 (Evidence)
Entrez Gene 66917 (Evidence)
DFCI TC1648114, TC1631921, TC1574669
DoTS DT.40176626, DT.492688, DT.94378477
NIA Mouse Gene Index U042952
Consensus CDS Project CCDS22842.1
International Mouse Phenotyping Consortium Status Chordc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001774 Ensembl Gene Model | MGI Sequence Detail 21734 C57BL/6J ±  kb
transcript ENSMUST00000001825 Ensembl | MGI Sequence Detail 2205 Not Applicable 
polypeptide ENSMUSP00000001825 Ensembl | MGI Sequence Detail 331 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(106 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007052 CS-like domain
InterPro IPR007051 Cysteine/histidine-rich domain
InterPro IPR008978 HSP20-like chaperone
Protein Ontology PR:000005445 cysteine and histidine-rich domain-containing protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:197112 Hong TJ, et al., Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1. J Biol Chem. 2013 Jan 4;288(1):215-22
All references(35)
Other
accession IDs
MGI:2142930

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory