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Cops9 Gene Detail
Summary
  • Symbol
    Cops9
  • Name
    COP9 signalosome subunit 9
  • Synonyms
    1110002M09Rik, Myeov2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914165
    NCBI Gene: 66915
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:92564867-92569707 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 46.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914165
protein coding gene Chr1:92564867-92569707 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016324
protein coding gene Chr1:94230530-94235370 (-)
A/J MGP_AJ_G0016305
protein coding gene Chr1:90853519-90858359 (-)
AKR/J MGP_AKRJ_G0016266
protein coding gene Chr1:93540831-93545671 (-)
BALB/cJ MGP_BALBcJ_G0016261
protein coding gene Chr1:91019993-91024833 (-)
C3H/HeJ MGP_C3HHeJ_G0016090
protein coding gene Chr1:93790705-93795545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016720
protein coding gene Chr1:97827201-97832041 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014438
protein coding gene Chr1:85103209-85108020 (-)
CAST/EiJ MGP_CASTEiJ_G0015673
protein coding gene Chr1:93101217-93106107 (-)
CBA/J MGP_CBAJ_G0016064
protein coding gene Chr1:100988500-100993340 (-)
DBA/2J MGP_DBA2J_G0016169
protein coding gene Chr1:90053026-90057866 (-)
FVB/NJ MGP_FVBNJ_G0016168
protein coding gene Chr1:89111222-89116062 (-)
LP/J MGP_LPJ_G0016240
protein coding gene Chr1:95417715-95422555 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016193
protein coding gene Chr1:104128538-104133378 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016759
protein coding gene Chr1:93551435-93556275 (-)
PWK/PhJ MGP_PWKPhJ_G0015458
protein coding gene Chr1:89472846-89477732 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015242
protein coding gene Chr1:92495815-92500603 (-)
WSB/EiJ MGP_WSBEiJ_G0015733
protein coding gene Chr1:93360614-93365377 (-)



Homology
more
  • Human Ortholog
    COPS9, COP9 signalosome subunit 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COPS9, COP9 signalosome subunit 9
  • Synonyms
    CSNAP, MYEOV2
  • Links
    NCBI Gene ID: 150678
    neXtProt AC: NX_Q8WXC6
    UniProt: Q8WXC6

  • Chr Location
    2q37.3; chr2:240126548-240136807 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Cops9
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66915 NCBI Gene Model | MGI Sequence Detail 4841 C57BL/6J ±  kb
transcript NR_028108 RefSeq | MGI Sequence Detail 760 C57BL/6  
polypeptide Q3U898 UniProt | EBI | MGI Sequence Detail 57 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory