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Vps28 Gene Detail
Summary
  • Symbol
    Vps28
  • Name
    vacuolar protein sorting 28
  • Synonyms
    1110014J03Rik, D730005C08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914164
    NCBI Gene: 66914
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76506286-76510284 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914164
 protein coding gene Chr15:76506286-76510286 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    VPS28, VPS28 subunit of ESCRT-I
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VPS28, VPS28 subunit of ESCRT-I
  • Synonyms
    CIIA
  • Links
    NCBI Gene ID: 51160
    neXtProt AC: NX_Q9UK41
    UniProt: Q9UK41

  • Chr Location
    8q24.3; chr8:144423601-144428563 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    136
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66914 NCBI Gene Model | MGI Sequence Detail 3999 C57BL/6J ±  kb
transcript NM_001305668 RefSeq | MGI Sequence Detail 1042 C57BL/6  
polypeptide Q9D1C8 UniProt | EBI | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000017329 vacuolar protein sorting-associated protein 28
    (term hierarchy)
  • InterPro Domains
    IPR037202 ESCRT assembly domain
    IPR007143 Vacuolar protein sorting-associated Vps28
    IPR017899 Vacuolar protein sorting-associated, VPS28, C-terminal
    IPR017898 Vacuolar protein sorting-associated, VPS28, N-terminal
    IPR037206 VPS28, C-terminal domain superfamily
    IPR038358 VPS28, N-terminal domain superfamily
Molecular
Reagents
less
  • All nucleic 137
    cDNA 137

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915536, MGI:2146076
References
more
  • Summaries
    All 60
    Diseases 1
    Gene Ontology 9
    Phenotypes 30
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory