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Crnkl1 Gene Detail
Summary
  • Symbol
    Crnkl1
  • Name
    crooked neck pre-mRNA splicing factor 1
  • Synonyms
    1200013P10Rik, 5730590A01Rik, crn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914127
    NCBI Gene: 66877
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:145917482-145934700 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 71.28 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914127
protein coding gene Chr2:145917479-145935014 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026596
protein coding gene Chr2:150085659-150103092 (-)
A/J MGP_AJ_G0026560
protein coding gene Chr2:144018057-144034106 (-)
AKR/J MGP_AKRJ_G0026534
protein coding gene Chr2:148192923-148210300 (-)
BALB/cJ MGP_BALBcJ_G0026572
protein coding gene Chr2:144441900-144459239 (-)
C3H/HeJ MGP_C3HHeJ_G0026315
protein coding gene Chr2:148674017-148691305 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027017
protein coding gene Chr2:154522781-154540160 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024394
protein coding gene Chr2:138136727-138154109 (-)
CAST/EiJ MGP_CASTEiJ_G0025776
protein coding gene Chr2:149028965-149046257 (-)
CBA/J MGP_CBAJ_G0026295
protein coding gene Chr2:160131041-160148370 (-)
DBA/2J MGP_DBA2J_G0026429
protein coding gene Chr2:143309142-143326581 (-)
FVB/NJ MGP_FVBNJ_G0026393
protein coding gene Chr2:141853831-141871083 (-)
LP/J MGP_LPJ_G0026533
protein coding gene Chr2:150277936-150295319 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026413
protein coding gene Chr2:164330218-164347514 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027072
protein coding gene Chr2:148185726-148203096 (-)
PWK/PhJ MGP_PWKPhJ_G0025511
protein coding gene Chr2:142981670-142999437 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025312
protein coding gene Chr2:147173653-147192266 (-)
WSB/EiJ MGP_WSBEiJ_G0025849
protein coding gene Chr2:149122288-149139580 (-)



Homology
more
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLF, Clf1, CRN, HCRN, MSTP021, SYF3
  • Links
    NCBI Gene ID: 51340
    neXtProt AC: NX_Q9BZJ0
    UniProt: Q9BZJ0

  • Chr Location
    20p11.23; chr20:20034361-20056046 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6462
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CRNKL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66877 NCBI Gene Model | MGI Sequence Detail 17219 C57BL/6J ±  kb
transcript NM_025820 RefSeq | MGI Sequence Detail 3111 C57BL/6  
polypeptide P63154 UniProt | EBI | MGI Sequence Detail 690 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 129
    cDNA 128
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924260, MGI:2139502
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory