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Crnkl1 Gene Detail
Summary
  • Symbol
    Crnkl1
  • Name
    Crn, crooked neck-like 1 (Drosophila)
  • Synonyms
    1200013P10Rik, 5730590A01Rik, crn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914127
    NCBI Gene: 66877
Location & Maps
more
  • Sequence Map
    Chr2:145917479-145935014 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17536 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 71.28 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLF, Clf1, CRN, HCRN, MSTP021, SYF3
  • Links
    NCBI Gene ID: 51340
    neXtProt AC: NX_Q9BZJ0

  • Chr Location
    20p11.2; chr20:20034361-20056046 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6462
    1 human;1 mouse;2 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CRNKL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Crnkl1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004058 VEGA Gene Model | MGI Sequence Detail 17536 C57BL/6J ±  kb
transcript OTTMUST00000009057 VEGA | MGI Sequence Detail 3428 Not Applicable  
polypeptide OTTMUSP00000004398 VEGA | MGI Sequence Detail 690 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    202 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005890 crooked neck-like protein 1
  • InterPro Domains
    IPR003107 HAT (Half-A-TPR) repeat
    IPR011990 Tetratricopeptide-like helical domain
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
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  • All nucleic 128
    cDNA 127
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924260, MGI:2139502
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:141291 Tamplin OJ, et al., Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory