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Ncbp3 Gene Detail
Summary
  • Symbol
    Ncbp3
  • Name
    nuclear cap binding subunit 3
  • Synonyms
    1200014J11Rik, C130061O14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914124
    NCBI Gene: 66874
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:73047867-73083579 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.16 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    288 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914124
protein coding gene Chr11:73047783-73089317 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018650
protein coding gene Chr11:73716727-73760137 (+)
A/J MGP_AJ_G0018618
protein coding gene Chr11:70949375-70990484 (+)
AKR/J MGP_AKRJ_G0018587
protein coding gene Chr11:73110375-73156827 (+)
BALB/cJ MGP_BALBcJ_G0018590
protein coding gene Chr11:71251376-71294987 (+)
C3H/HeJ MGP_C3HHeJ_G0018403
protein coding gene Chr11:73073344-73114439 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019041
protein coding gene Chr11:75935084-75990461 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016684
protein coding gene Chr11:67760674-67800720 (+)
CAST/EiJ MGP_CASTEiJ_G0017958
protein coding gene Chr11:73451668-73495577 (+)
CBA/J MGP_CBAJ_G0018375
protein coding gene Chr11:79308682-79359527 (+)
DBA/2J MGP_DBA2J_G0018484
protein coding gene Chr11:70579406-70620612 (+)
FVB/NJ MGP_FVBNJ_G0018475
protein coding gene Chr11:70124391-70166896 (+)
LP/J MGP_LPJ_G0018555
protein coding gene Chr11:74211445-74257799 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018498
protein coding gene Chr11:79829995-79875264 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019083
protein coding gene Chr11:73306010-73347427 (+)
PWK/PhJ MGP_PWKPhJ_G0017731
protein coding gene Chr11:71216411-71257481 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017521
protein coding gene Chr11:73016393-73059973 (+)
WSB/EiJ MGP_WSBEiJ_G0018012
protein coding gene Chr11:73050778-73095002 (+)



Homology
more
  • Human Ortholog
    NCBP3, nuclear cap binding subunit 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NCBP3, nuclear cap binding subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C17orf85, ELG, HSA277841
  • Links
    NCBI Gene ID: 55421
    neXtProt AC: NX_Q53F19
    UniProt: Q53F19

  • Chr Location
    17p13.2; chr17:3806748-3846251 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10231
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NCBP3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66874 NCBI Gene Model | MGI Sequence Detail 35713 C57BL/6J ±  kb
transcript NM_025818 RefSeq | MGI Sequence Detail 6284 C57BL/6  
polypeptide Q8BZR9 UniProt | EBI | MGI Sequence Detail 615 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR019416 Nuclear cap-binding protein subunit 3
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Molecular
Reagents
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  • All nucleic 72
    cDNA 72

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144640
References
more
  • Summaries
    All 42
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:226985 Gebhardt A, et al., mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015;6:8192

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory