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Serbp1 Gene Detail
Summary
  • Symbol
    Serbp1
  • Name
    serpine1 mRNA binding protein 1
  • Synonyms
    1200009K13Rik, 9330147J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914120
    NCBI Gene: 66870
  • Gene Overview
    MyGene.info: SERBP1
Location & Maps
more
  • Sequence Map
    Chr6:67238176-67297736 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      59561 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 30.80 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SERBP1, SERPINE1 mRNA binding protein 1
  • Vertebrate Orthologs
    3
  • Human Ortholog
    SERBP1, SERPINE1 mRNA binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-55, CHD3IP, HABP4L, PAIRBP1, PAI-RBP1
  • Links
    NCBI Gene ID: 26135
    neXtProt AC: NX_Q8NC51
    UniProt: Q8NC51

  • Chr Location
    1p31.3; chr1:67407810-67430440 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    9
  • Tissues
    4
  • cDNA Data
    26
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057415 VEGA Gene Model | MGI Sequence Detail 59561 C57BL/6J ±  kb
transcript OTTMUST00000141236 VEGA | MGI Sequence Detail 15474 Not Applicable  
polypeptide OTTMUSP00000073837 VEGA | MGI Sequence Detail 407 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    404 from dbSNP Build 142
Protein
Information
less
  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000014665 plasminogen activator inhibitor 1 RNA-binding protein
    (term hierarchy)
  • InterPro Domains
    IPR006861 Hyaluronan/mRNA-binding protein
    IPR032381 Intracellular hyaluronan-binding protein 4, N-terminal domain
    IPR027205 Plasminogen activator inhibitor 1 RNA-binding protein
Molecular
Reagents
less
  • All nucleic 27
    cDNA 26
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2141530, MGI:2444088
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:204704 Chew TG, et al., A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption. PLoS One. 2013;8(7):e69764
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/20/2017
MGI 6.10 		The Jackson Laboratory