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Trim35 Gene Detail
Summary
  • Symbol
    Trim35
  • Name
    tripartite motif-containing 35
  • Synonyms
    0710005M05Rik, A430106H13Rik, Hls5, Mair, mKIAA1098
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914104
    NCBI Gene: 66854
Location & Maps
more
  • Sequence Map
    Chr14:66297031-66311424 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14394 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.44 cM, cytoband D1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TRIM35, tripartite motif containing 35
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TRIM35, tripartite motif containing 35
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HLS5, MAIR
  • Links
    NCBI Gene ID: 23087
    neXtProt AC: NX_Q9UPQ4

  • Chr Location
    8p21.2; chr8:27284886-27311319 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Trim35
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027825 VEGA Gene Model | MGI Sequence Detail 14394 C57BL/6J ±  kb
transcript OTTMUST00000068880 VEGA | MGI Sequence Detail 3678 Not Applicable  
polypeptide OTTMUSP00000034911 VEGA | MGI Sequence Detail 516 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 5
Other
Accession IDs
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MGI:1925036, MGI:2145786
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:65653 Wertz K, et al., Large-scale screen for genes involved in gonad development. Mech Dev. 2000 Nov;98(1-2):51-70
  • Latest
    J:221417 Wang Y, et al., TRIM35 negatively regulates TLR7- and TLR9-mediated type I interferon production by targeting IRF7. FEBS Lett. 2015 May 22;589(12):1322-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory