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Hint3 Gene Detail
Summary
  • Symbol
    Hint3
  • Name
    histidine triad nucleotide binding protein 3
  • Synonyms
    0610010I17Rik, HINT4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914097
    NCBI Gene: 66847
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:30608207-30629401 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 17.10 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914097
protein coding gene Chr10:30608141-30629632 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017117
protein coding gene Chr10:28817095-28827433 (-)
A/J MGP_AJ_G0017094
protein coding gene Chr10:27974458-27984767 (-)
AKR/J MGP_AKRJ_G0017054
protein coding gene Chr10:28414595-28424931 (-)
BALB/cJ MGP_BALBcJ_G0017057
protein coding gene Chr10:28053869-28064215 (-)
C3H/HeJ MGP_C3HHeJ_G0016877
protein coding gene Chr10:28682256-28692607 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017515
protein coding gene Chr10:29673779-29686622 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015213
protein coding gene Chr10:26418104-26427824 (-)
CAST/EiJ MGP_CASTEiJ_G0016456
protein coding gene Chr10:28742375-28756258 (-)
CBA/J MGP_CBAJ_G0016851
protein coding gene Chr10:31092333-31102521 (-)
DBA/2J MGP_DBA2J_G0016956
protein coding gene Chr10:27646796-27657006 (-)
FVB/NJ MGP_FVBNJ_G0016951
protein coding gene Chr10:27263459-27274962 (-)
LP/J MGP_LPJ_G0017033
protein coding gene Chr10:28830233-28840407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016981
protein coding gene Chr10:31291994-31302332 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017551
protein coding gene Chr10:28327446-28338235 (-)
PWK/PhJ MGP_PWKPhJ_G0016238
protein coding gene Chr10:27415705-27426904 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016022
protein coding gene Chr10:28263236-28276890 (-)
WSB/EiJ MGP_WSBEiJ_G0016519
protein coding gene Chr10:28462416-28476021 (-)



Homology
more
  • Human Ortholog
    HINT3, histidine triad nucleotide binding protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HINT3, histidine triad nucleotide binding protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HINT4
  • Links
    NCBI Gene ID: 135114
    neXtProt AC: NX_Q9NQE9
    UniProt: Q9NQE9

  • Chr Location
    6q22.32; chr6:125956715-125980244 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12046
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HINT3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Hint3
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66847 NCBI Gene Model | MGI Sequence Detail 21195 C57BL/6J ±  kb
transcript NM_025798 RefSeq | MGI Sequence Detail 696 C57BL/6  
polypeptide Q9CPS6 UniProt | EBI | MGI Sequence Detail 165 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143774
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:246912 Ye A, et al., PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory