Cab39l MGI Mouse Gene Detail - MGI:1914081 - calcium binding protein 39-like

Symbol

Cab39l
Name

calcium binding protein 39-like
Synonyms

1500031K13Rik, 2810425O13Rik, 4930520C08Rik, MO2L

Feature Type

protein coding gene
IDs

MGI:1914081
NCBI Gene: 69008
Gene Overview

MyGene.info: CAB39L
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr14:59440955-59548903 bp, + strand
From NCBI annotation of GRCm38

View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 31.48 cM
Mapping Data

2 experiments

SNPs within 2kb

430 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914081	protein coding gene	Chr14:59440955-59585764 (.)
129S1/SvImJ	MGP_129S1SvImJ_G0021425	protein coding gene	Chr14:53742057-53864503 (+)
A/J	MGP_AJ_G0021384	protein coding gene	Chr14:52614933-52724827 (+)
AKR/J	MGP_AKRJ_G0021359	protein coding gene	Chr14:54474929-54598357 (+)
BALB/cJ	MGP_BALBcJ_G0021389	protein coding gene	Chr14:52576391-52686733 (+)
C3H/HeJ	MGP_C3HHeJ_G0021167	protein coding gene	Chr14:54133478-54255524 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021828	protein coding gene	Chr14:56413408-56543067 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019368	protein coding gene	Chr14:50672456-50762563 (+)
CAST/EiJ	MGP_CASTEiJ_G0020683	protein coding gene	Chr14:50545754-50664663 (+)
CBA/J	MGP_CBAJ_G0021134	protein coding gene	Chr14:58006245-58136706 (+)
DBA/2J	MGP_DBA2J_G0021257	protein coding gene	Chr14:52285069-52396840 (+)
FVB/NJ	MGP_FVBNJ_G0021235	protein coding gene	Chr14:51699813-51807697 (+)
LP/J	MGP_LPJ_G0021331	protein coding gene	Chr14:54771564-54891118 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021264	protein coding gene	Chr14:57420726-57543734 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021851	protein coding gene	Chr14:53622618-53736158 (+)
PWK/PhJ	MGP_PWKPhJ_G0020427	protein coding gene	Chr14:48924055-49037418 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020260	protein coding gene	Chr14:49630859-49740933 (+)
WSB/EiJ	MGP_WSBEiJ_G0020736	protein coding gene	Chr14:53938833-54056558 (+)

Human Ortholog

CAB39L, calcium binding protein 39 like

Vertebrate Orthologs

10

Human Ortholog

CAB39L, calcium binding protein 39 like
Orthology source: HomoloGene, HGNC
Synonyms

bA103J18.3, MO25-BETA, MO2L
Links

HGNC:20290

NCBI Gene ID: 81617

neXtProt AC: NX_Q9H9S4

UniProt: Q9H9S4
Chr Location

13q14.2; chr13:49308628-49444346 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 69422
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: CAB39L
Protein SuperFamily

hypothetical protein, Saccharomyces cerevisiae YKL189w type
Gene Tree

Cab39l

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
16 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

20
Chemically induced (other)

1
Gene trapped

15
Targeted

4
Genomic Mutations

1 involving Cab39l
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

4
GO References

2

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

88
Tissues

57
cDNA Data

98
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cab39l

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Cab39l interacts with 212 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

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All Sequences

62
RefSeq

10
UniProt

3
CCDS

CCDS27171.1
UniGene

179091

Ensembl

ENSMUSG00000021981 (Evidence)
NCBI Gene

69008

			Length	Strain/Species	Flank
genomic	69008	NCBI Gene Model \| MGI Sequence Detail	107949	C57BL/6J	± kb
transcript	NM_001360591	RefSeq \| MGI Sequence Detail	3113	C57BL/6
polypeptide	Q9DB16	UniProt \| EBI \| MGI Sequence Detail	337	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000004928 calcium-binding protein 39-like

(term hierarchy)
InterPro Domains

IPR011989 Armadillo-like helical

IPR016024 Armadillo-type fold

IPR013878 Mo25-like

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All nucleic 98

cDNA 98

Microarray probesets 6

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MGI:1916258, MGI:1922871, MGI:2145574

Summaries

All 39

Developmental Gene Expression 2

Gene Ontology 2

Phenotypes 16
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

TSS for Cab39l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125903	Chr14:59440572-59440582 (+)	-378 bp
Tssr125904	Chr14:59440947-59440996 (+)	17 bp
Tssr125905	Chr14:59478835-59478852 (+)	37,889 bp
Tssr125906	Chr14:59478864-59478923 (+)	37,939 bp
Tssr125907	Chr14:59478932-59478991 (+)	38,007 bp
Tssr125908	Chr14:59479014-59479032 (+)	38,068 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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