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Ccdc109b Gene Detail
Summary
  • Symbol
    Ccdc109b
  • Name
    coiled-coil domain containing 109B
  • Synonyms
    9030408N13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914065
    NCBI Gene: 66815
Location & Maps
more
  • Sequence Map
    Chr3:129914960-129970206 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      55247 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 59.56 cM, cytoband H1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MCUB, mitochondrial calcium uniporter dominant negative beta subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MCUB, mitochondrial calcium uniporter dominant negative beta subunit
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CCDC109B
  • Links
    NCBI Gene ID: 55013
    neXtProt AC: NX_Q9NWR8

  • Chr Location
    4q25; chr4:109560199-109688645 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    6
  • Genomic Mutations
    2 involving Ccdc109b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026525 VEGA Gene Model | MGI Sequence Detail 55247 C57BL/6J ±  kb
transcript OTTMUST00000065624 VEGA | MGI Sequence Detail 1318 Not Applicable  
polypeptide OTTMUSP00000032728 VEGA | MGI Sequence Detail 345 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    267 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000030361 coiled-coil domain-containing protein 109B
  • InterPro Domains
    IPR006769 Coiled-coil domain containing protein 109, C-terminal
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:201635 Raffaello A, et al., The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. EMBO J. 2013 Aug 28;32(17):2362-76

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory