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Adat2 Gene Detail
Summary
  • Symbol
    Adat2
  • Name
    adenosine deaminase, tRNA-specific 2
  • Synonyms
    4933426M09Rik, Deadc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914007
    NCBI Gene: 66757
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:13428651-13439120 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 4.94 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914007
protein coding gene Chr10:13428638-13439120 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017024
protein coding gene Chr10:10972959-10984529 (+)
A/J MGP_AJ_G0017002
protein coding gene Chr10:10557041-10567522 (+)
AKR/J MGP_AKRJ_G0016966
protein coding gene Chr10:10805318-10815781 (+)
BALB/cJ MGP_BALBcJ_G0016960
protein coding gene Chr10:10580501-10590981 (+)
C3H/HeJ MGP_C3HHeJ_G0016785
protein coding gene Chr10:10958744-10969220 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017422
protein coding gene Chr10:11260320-11270748 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015127
protein coding gene Chr10:9831867-9845652 (+)
CAST/EiJ MGP_CASTEiJ_G0016367
protein coding gene Chr10:10836733-10847266 (+)
CBA/J MGP_CBAJ_G0016757
protein coding gene Chr10:11693286-11703747 (+)
DBA/2J MGP_DBA2J_G0016865
protein coding gene Chr10:10467867-10478298 (+)
FVB/NJ MGP_FVBNJ_G0016860
protein coding gene Chr10:10297945-10308404 (+)
LP/J MGP_LPJ_G0016940
protein coding gene Chr10:10828111-10838625 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016890
protein coding gene Chr10:11579508-11591150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017460
protein coding gene Chr10:10688072-10698537 (+)
PWK/PhJ MGP_PWKPhJ_G0016152
protein coding gene Chr10:10350167-10360765 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015935
protein coding gene Chr10:10838138-10862681 (+)
WSB/EiJ MGP_WSBEiJ_G0016429
protein coding gene Chr10:10730981-10742253 (+)



Homology
more
  • Human Ortholog
    ADAT2, adenosine deaminase tRNA specific 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADAT2, adenosine deaminase tRNA specific 2
  • Synonyms
    DEADC1, dJ20N2, dJ20N2.1, TAD2
  • Links
    NCBI Gene ID: 134637
    neXtProt AC: NX_Q7Z6V5
    UniProt: Q7Z6V5

  • Chr Location
    6q24.2; chr6:143422832-143450695 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66757 NCBI Gene Model | MGI Sequence Detail 10470 C57BL/6J ±  kb
transcript NM_025748 RefSeq | MGI Sequence Detail 1453 C57BL/6  
polypeptide Q6P6J0 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:308112 Ramos-Morales E, et al., The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res. 2021 Jun 21;49(11):6529-6548

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory