About   Help   FAQ
Actr2 Gene Detail
Summary
  • Symbol
    Actr2
  • Name
    ARP2 actin-related protein 2
  • Synonyms
    4921510D23Rik, Arp2, D6Ertd746e, MGC:36604
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913963
    NCBI Gene: 66713
  • Gene Overview
    MyGene.info: ACTR2
Location & Maps
more
  • Sequence Map
    Chr11:20062304-20112913 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      50610 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ACTR2, ARP2 actin-related protein 2 homolog (yeast)
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ACTR2, ARP2 actin-related protein 2 homolog (yeast)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ARP2
  • Links
    NCBI Gene ID: 10097
    neXtProt AC: NX_P61160

  • Chr Location
    2p14; chr2:65227695-65271253 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4181
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: ACTR2
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    43
  • Chemically induced (other)
    1
  • Gene trapped
    40
  • Targeted
    2
  • Genomic Mutations
    1 involving Actr2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005221 VEGA Gene Model | MGI Sequence Detail 50610 C57BL/6J ±  kb
transcript OTTMUST00000011649 VEGA | MGI Sequence Detail 3631 Not Applicable  
polypeptide OTTMUSP00000005405 VEGA | MGI Sequence Detail 394 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    452 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1289149, MGI:2144001
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:217819 Yang W, et al., Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling. Biochem J. 2014 Dec 1;464(2):179-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory