About   Help   FAQ
Ndufaf3 Gene Detail
Summary
  • Symbol
    Ndufaf3
  • Name
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
  • Synonyms
    4733401H18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913956
    NCBI Gene: 66706
  • Gene Overview
    MyGene.info: NDUFAF3
Location & Maps
more
  • Sequence Map
    Chr9:108565537-108567434 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1898 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.50 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2P1, C3orf60, E3-3
  • Links
    NCBI Gene ID: 25915
    neXtProt AC: NX_Q9BU61

  • Chr Location
    3p21.31; chr3:49020475-49023495 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NDUFAF3 associations

Human Disease Mouse Models
       Mitochondrial Complex I Deficiency   OMIM: 252010
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    16
  • Gene trapped
    15
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050764 VEGA Gene Model | MGI Sequence Detail 1898 C57BL/6J ±  kb
transcript OTTMUST00000128670 VEGA | MGI Sequence Detail 1487 Not Applicable  
polypeptide OTTMUSP00000069195 VEGA | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    8 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032370 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3
  • InterPro Domains
    IPR007523 NDUFAF3/Mth938 domain-containing protein
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory