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Nipa2 Gene Detail
Summary
  • Symbol
    Nipa2
  • Name
    non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
  • Synonyms
    2600017P10Rik, 3830408P04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913918
    NCBI Gene: 93790
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:55581035-55612224 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 33.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    661 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913918
 protein coding gene Chr7:55581014-55612241 (-)
129S1/SvImJ ENSMUSG00200008581
 protein coding gene Chr7:43068561-43092634 (-)
A/J ENSMUSG00195010609
 protein coding gene Chr7:47230562-47254634 (-)
AKR/J ENSMUSG00220011055
 protein coding gene Chr7:41539113-41563186 (-)
BALB/cJ ENSMUSG00180010282
 protein coding gene Chr7:44094310-44118346 (-)
C3H/HeJ ENSMUSG00175003252
 protein coding gene Chr7:44587733-44611806 (-)
C57BL/6NJ ENSMUSG00215001878
 protein coding gene Chr7:43902859-43934047 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029805
 protein coding gene Chr7:58559913-58583142 (-)
CAST/EiJ ENSTCUG00005022181
 protein coding gene Chr7:47457100-47481320 (-)
CBA/J ENSMUSG00210017394
 protein coding gene Chr7:44969433-44993505 (-)
DBA/2J ENSMUSG00185027889
 protein coding gene Chr7:48860813-48884851 (-)
FVB/NJ ENSMUSG00205001375
 protein coding gene Chr7:44667866-44691938 (-)
JF1/MsJ ENSUMUG00000012908
 protein coding gene Chr7:53666855-53690884 (-)
LP/J ENSMUSG00230005316
 protein coding gene Chr7:54407974-54432046 (-)
NOD/ShiLtJ ENSMUSG00190003553
 protein coding gene Chr7:45000489-45024561 (-)
NZO/HlLtJ ENSMUSG00225009711
 protein coding gene Chr7:52586910-52610981 (-)
PWK/PhJ ENSLUMG00010002243
 protein coding gene Chr7:43601708-43625758 (-)
SPRET/EiJ ENSMSPG00010001399
 protein coding gene Chr7:43584043-43611155 (-)
WSB/EiJ ENSIUOG00005005285
 protein coding gene Chr7:45286632-45310711 (-)



Homology
more
  • Human Ortholog
    NIPA2, NIPA magnesium transporter 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NIPA2, NIPA magnesium transporter 2
  • Synonyms
    SLC57A2
  • Links
    NCBI Gene ID: 81614
    UniProt: Q8N8Q9

  • Chr Location
    15q11.2; chr15:22838625-22869362 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    19
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030452 Ensembl Gene Model | MGI Sequence Detail 31190 C57BL/6J ±  kb
transcript ENSMUST00000117812 Ensembl | MGI Sequence Detail 3039 Not Applicable  
polypeptide ENSMUSP00000113727 Ensembl | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919319, MGI:1930918
References
more
  • Summaries
    All 40
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:297803 Zhao W, et al., NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis. Sci Rep. 2020 Feb 20;10(1):3078
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory